Revisiting the role of T cells in tumor regression

This note challenges the current idea that a key role of T cells in tumor regression is to directly kill tumor cells. It favors the view that TIL are keys but act indirectly by helping other immune cells to damage the tumor and its stroma.

Detalles Bibliográficos
Autores principales: Bercovici, Nadège, Trautmann, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Point of View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382877/
https://www.ncbi.nlm.nih.gov/pubmed/22737611
http://dx.doi.org/10.4161/onci.18800
_version_ 1782236565517369344
author Bercovici, Nadège
Trautmann, Alain
author_facet Bercovici, Nadège
Trautmann, Alain
author_sort Bercovici, Nadège
collection PubMed
description This note challenges the current idea that a key role of T cells in tumor regression is to directly kill tumor cells. It favors the view that TIL are keys but act indirectly by helping other immune cells to damage the tumor and its stroma.
format Online
Article
Text
id pubmed-3382877
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Landes Bioscience
record_format MEDLINE/PubMed
spelling pubmed-33828772012-06-26 Revisiting the role of T cells in tumor regression Bercovici, Nadège Trautmann, Alain Oncoimmunology Point of View This note challenges the current idea that a key role of T cells in tumor regression is to directly kill tumor cells. It favors the view that TIL are keys but act indirectly by helping other immune cells to damage the tumor and its stroma. Landes Bioscience 2012-05-01 /pmc/articles/PMC3382877/ /pubmed/22737611 http://dx.doi.org/10.4161/onci.18800 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Point of View
Bercovici, Nadège
Trautmann, Alain
Revisiting the role of T cells in tumor regression
title Revisiting the role of T cells in tumor regression
title_full Revisiting the role of T cells in tumor regression
title_fullStr Revisiting the role of T cells in tumor regression
title_full_unstemmed Revisiting the role of T cells in tumor regression
title_short Revisiting the role of T cells in tumor regression
title_sort revisiting the role of t cells in tumor regression
topic Point of View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382877/
https://www.ncbi.nlm.nih.gov/pubmed/22737611
http://dx.doi.org/10.4161/onci.18800
work_keys_str_mv AT bercovicinadege revisitingtheroleoftcellsintumorregression
AT trautmannalain revisitingtheroleoftcellsintumorregression

Ejemplares similares