A novel facet of tumor suppression by p53: Induction of tumor immunogenicity

Pharmacological reactivation of the p53 tumor suppressor is a promising strategy for anti-cancer therapy due to its high potential to elicit apoptosis or growth arrest in cancer cells. Recently we uncovered the mechanism of activation of the innate immune response by p53 upon its activation by small...

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Autores principales: Li, Hai, Lakshmikanth, Tadepally, Carbone, Ennio, Selivanova, Galina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382884/
https://www.ncbi.nlm.nih.gov/pubmed/22754780
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author Li, Hai
Lakshmikanth, Tadepally
Carbone, Ennio
Selivanova, Galina
author_facet Li, Hai
Lakshmikanth, Tadepally
Carbone, Ennio
Selivanova, Galina
author_sort Li, Hai
collection PubMed
description Pharmacological reactivation of the p53 tumor suppressor is a promising strategy for anti-cancer therapy due to its high potential to elicit apoptosis or growth arrest in cancer cells. Recently we uncovered the mechanism of activation of the innate immune response by p53 upon its activation by small molecules.
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spelling pubmed-33828842012-07-01 A novel facet of tumor suppression by p53: Induction of tumor immunogenicity Li, Hai Lakshmikanth, Tadepally Carbone, Ennio Selivanova, Galina Oncoimmunology Author's View Pharmacological reactivation of the p53 tumor suppressor is a promising strategy for anti-cancer therapy due to its high potential to elicit apoptosis or growth arrest in cancer cells. Recently we uncovered the mechanism of activation of the innate immune response by p53 upon its activation by small molecules. Landes Bioscience 2012-07-01 /pmc/articles/PMC3382884/ /pubmed/22754780 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Li, Hai
Lakshmikanth, Tadepally
Carbone, Ennio
Selivanova, Galina
A novel facet of tumor suppression by p53: Induction of tumor immunogenicity
title A novel facet of tumor suppression by p53: Induction of tumor immunogenicity
title_full A novel facet of tumor suppression by p53: Induction of tumor immunogenicity
title_fullStr A novel facet of tumor suppression by p53: Induction of tumor immunogenicity
title_full_unstemmed A novel facet of tumor suppression by p53: Induction of tumor immunogenicity
title_short A novel facet of tumor suppression by p53: Induction of tumor immunogenicity
title_sort novel facet of tumor suppression by p53: induction of tumor immunogenicity
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382884/
https://www.ncbi.nlm.nih.gov/pubmed/22754780
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