Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells

Although primarily defined by their cardinal antigen-presenting function, dendritic cells (DCs) are also equipped with cytotoxic properties. We have recently reported that DCs activated by IFNγ-secreting Th-1 lymphocytes can kill cancer cells and subsequently present the acquired tumor-derived antig...

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Detalles Bibliográficos
Autores principales: Larmonier, Nicolas, Bonnotte, Bernard, Katsanis, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382885/
https://www.ncbi.nlm.nih.gov/pubmed/22754789
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author Larmonier, Nicolas
Bonnotte, Bernard
Katsanis, Emmanuel
author_facet Larmonier, Nicolas
Bonnotte, Bernard
Katsanis, Emmanuel
author_sort Larmonier, Nicolas
collection PubMed
description Although primarily defined by their cardinal antigen-presenting function, dendritic cells (DCs) are also equipped with cytotoxic properties. We have recently reported that DCs activated by IFNγ-secreting Th-1 lymphocytes can kill cancer cells and subsequently present the acquired tumor-derived antigens to T lymphocytes both in vitro and in vivo.
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spelling pubmed-33828852012-07-01 Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells Larmonier, Nicolas Bonnotte, Bernard Katsanis, Emmanuel Oncoimmunology Author's View Although primarily defined by their cardinal antigen-presenting function, dendritic cells (DCs) are also equipped with cytotoxic properties. We have recently reported that DCs activated by IFNγ-secreting Th-1 lymphocytes can kill cancer cells and subsequently present the acquired tumor-derived antigens to T lymphocytes both in vitro and in vivo. Landes Bioscience 2012-07-01 /pmc/articles/PMC3382885/ /pubmed/22754789 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Larmonier, Nicolas
Bonnotte, Bernard
Katsanis, Emmanuel
Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells
title Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells
title_full Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells
title_fullStr Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells
title_full_unstemmed Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells
title_short Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells
title_sort cytotoxic and antigen presenting functions of t helper-1-activated dendritic cells
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382885/
https://www.ncbi.nlm.nih.gov/pubmed/22754789
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AT katsanisemmanuel cytotoxicandantigenpresentingfunctionsofthelper1activateddendriticcells

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