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Know thy enemy: Why are tumor-infiltrating regulatory T cells so deleterious?

We recently described hypoxia as one of the leading mechanism for the recruitment of regulatory T cells (Treg) through CCL28 chemokine in ovarian cancer. Treg promote progression of cancer through tumor-specific immune paralysis but also reprogramming of angiogenesis. We review these mechanisms and...

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Detalles Bibliográficos
Autores principales:	Facciabene, Andrea, Santoro, Stephen, Coukos, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382887/ https://www.ncbi.nlm.nih.gov/pubmed/22754792

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