Immune mediated mechanisms of melanocyte destruction: Paving the way for efficient immunotherapeutic strategies against melanoma

Insights into immune reactions against benign and malignant melanocytes may help the development of more efficient immunotherapeutic treatments for melanoma. The interplay between an active systemic antitumor immunity and a responsive local tumor environment is crucial to achieve effective clinical...

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Autores principales: Speeckaert, Reinhart, Van Geel, Nanja, Lambert, Jo, Boone, Barbara, Chevolet, Ines, Van Gele, Mireille, Speeckaert, Marijn M., Brochez, Lieve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382893/
https://www.ncbi.nlm.nih.gov/pubmed/22754773
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author Speeckaert, Reinhart
Van Geel, Nanja
Lambert, Jo
Boone, Barbara
Chevolet, Ines
Van Gele, Mireille
Speeckaert, Marijn M.
Brochez, Lieve
author_facet Speeckaert, Reinhart
Van Geel, Nanja
Lambert, Jo
Boone, Barbara
Chevolet, Ines
Van Gele, Mireille
Speeckaert, Marijn M.
Brochez, Lieve
author_sort Speeckaert, Reinhart
collection PubMed
description Insights into immune reactions against benign and malignant melanocytes may help the development of more efficient immunotherapeutic treatments for melanoma. The interplay between an active systemic antitumor immunity and a responsive local tumor environment is crucial to achieve effective clinical responses. Increasing evidence confirms this strategy can lead to an adequate and durable immunosurveillance of melanocytes.
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spelling pubmed-33828932012-07-01 Immune mediated mechanisms of melanocyte destruction: Paving the way for efficient immunotherapeutic strategies against melanoma Speeckaert, Reinhart Van Geel, Nanja Lambert, Jo Boone, Barbara Chevolet, Ines Van Gele, Mireille Speeckaert, Marijn M. Brochez, Lieve Oncoimmunology Author's View Insights into immune reactions against benign and malignant melanocytes may help the development of more efficient immunotherapeutic treatments for melanoma. The interplay between an active systemic antitumor immunity and a responsive local tumor environment is crucial to achieve effective clinical responses. Increasing evidence confirms this strategy can lead to an adequate and durable immunosurveillance of melanocytes. Landes Bioscience 2012-07-01 /pmc/articles/PMC3382893/ /pubmed/22754773 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Speeckaert, Reinhart
Van Geel, Nanja
Lambert, Jo
Boone, Barbara
Chevolet, Ines
Van Gele, Mireille
Speeckaert, Marijn M.
Brochez, Lieve
Immune mediated mechanisms of melanocyte destruction: Paving the way for efficient immunotherapeutic strategies against melanoma
title Immune mediated mechanisms of melanocyte destruction: Paving the way for efficient immunotherapeutic strategies against melanoma
title_full Immune mediated mechanisms of melanocyte destruction: Paving the way for efficient immunotherapeutic strategies against melanoma
title_fullStr Immune mediated mechanisms of melanocyte destruction: Paving the way for efficient immunotherapeutic strategies against melanoma
title_full_unstemmed Immune mediated mechanisms of melanocyte destruction: Paving the way for efficient immunotherapeutic strategies against melanoma
title_short Immune mediated mechanisms of melanocyte destruction: Paving the way for efficient immunotherapeutic strategies against melanoma
title_sort immune mediated mechanisms of melanocyte destruction: paving the way for efficient immunotherapeutic strategies against melanoma
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382893/
https://www.ncbi.nlm.nih.gov/pubmed/22754773
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