Cargando…

Hypoxia-inducible factor 1: A link between metabolism and T cell differentiation and a potential therapeutic target

Naïve T cells activated by antigen-presenting cells (APC) can be differentiated into at least four major types of T-helper (T(H)) cells: T(H)1, T(H)2, T(H)17 and inducible regulatory T cells (iTreg) based on their unique cytokine production profiles and characteristic functions.(1) T(H)1 produce int...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Fan, Barbi, Joseph, Pardoll, Drew M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382896/ https://www.ncbi.nlm.nih.gov/pubmed/22754770

Ejemplares similares

Potential therapeutic targets for hypoxia-induced pulmonary artery hypertension
por: Dong, Li, et al.
Publicado: (2014)

Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symporters
por: Marchiq, Ibtissam, et al.
Publicado: (2015)

Overexpression of hypoxia-inducible factor-1α in hidradenitis suppurativa: the link between deviated immunity and metabolism
por: Agamia, Naglaa Fathi, et al.
Publicado: (2023)

Hypoxia, HIF-1α, and COVID-19: from pathogenic factors to potential therapeutic targets
por: Serebrovska, Zoya O., et al.
Publicado: (2020)

YAP Attenuates CD8 T Cell-Mediated Anti-tumor Response
por: Lebid, Andriana, et al.
Publicado: (2020)

Special Issue: Hypoxia-Inducible Factors: Regulation and Therapeutic Potential
por: Hirota, Kiichi
Publicado: (2021)

Hypoxia-inducible factor (HIF): The link between obesity and COVID-19
por: AbdelMassih, Antoine, et al.
Publicado: (2021)

Therapeutic Targeting Hypoxia-Inducible Factor (HIF-1) in Cancer: Cutting Gordian Knot of Cancer Cell Metabolism
por: Sharma, Abhilasha, et al.
Publicado: (2022)

Therapeutic potential of topical administration of acriflavine against hypoxia-inducible factors for corneal fibrosis
por: Zhu, Shuyan, et al.
Publicado: (2022)

What are the links between hypoxia and Alzheimer’s disease?
por: Lall, Rahul, et al.
Publicado: (2019)

Mechanisms of metabolic memory and renal hypoxia as a therapeutic target in diabetic kidney disease
por: Hirakawa, Yosuke, et al.
Publicado: (2017)

Cancer Cell Metabolism in Hypoxia: Role of HIF-1 as Key Regulator and Therapeutic Target
por: Infantino, Vittoria, et al.
Publicado: (2021)

Corrigendum: Therapeutic potential of topical administration of acriflavine against hypoxia-inducible factors for corneal fibrosis
por: Zhu, Shuyan, et al.
Publicado: (2023)

Potential regulatory role of miRNA and mRNA link to metabolism affected by chronic intermittent hypoxia
por: Duan, Yanru, et al.
Publicado: (2022)

Immunotherapy earns its spot in the ranks of cancer therapy
por: Pardoll, Drew, et al.
Publicado: (2012)

The impact of hypoxia-inducible factors in the pathogenesis of kidney diseases: a link through cell metabolism
por: Foresto-Neto, Orestes, et al.
Publicado: (2023)

Overexpression of hypoxia-inducible factor and metabolic pathways: possible targets of cancer
por: Singh, Davinder, et al.
Publicado: (2017)

Hypoxia signaling in human diseases and therapeutic targets
por: Lee, Jae W., et al.
Publicado: (2019)

Advances in Understanding the Links between Metabolism and Autophagy in Acute Myeloid Leukemia: From Biology to Therapeutic Targeting
por: Saulle, Ernestina, et al.
Publicado: (2023)

Hypoxia-Inducible Factor-1 as a Therapeutic Target in Endometrial Cancer Management
por: Seeber, Laura M. S., et al.
Publicado: (2010)

Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma
por: Borsi, Enrica, et al.
Publicado: (2014)

Altered acetyl-CoA metabolism presents a new potential immunotherapy target in the obese lung microenvironment
por: Rosario, Spencer R., et al.
Publicado: (2022)

Potential therapeutic targets for atherosclerosis in sphingolipid metabolism
por: Yu, Zemou, et al.
Publicado: (2019)

Metabolic Reprogramming and Potential Therapeutic Targets in Lymphoma
por: Pang, Yuyang, et al.
Publicado: (2023)

Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor
por: Fukushima, Suguru, et al.
Publicado: (2017)

New insights into the links between hypoxia and iron homeostasis
por: Renassia, Cyril, et al.
Publicado: (2019)

Glioblastoma multiforme: Effect of hypoxia and hypoxia inducible factors on therapeutic approaches
por: Huang, Wen-Juan, et al.
Publicado: (2016)

Well-differentiated liver cancers reveal the potential link between ACE2 dysfunction and metabolic breakdown
por: Desquilles, Lise, et al.
Publicado: (2022)

Systemic Metabolism and Mitochondria in the Mechanism of Alzheimer’s Disease: Finding Potential Therapeutic Targets
por: Song, Meiying, et al.
Publicado: (2023)

Reframing the link between metabolism and NLRP3 inflammasome: therapeutic opportunities
por: Ortega, Miguel A., et al.
Publicado: (2023)

Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia
por: Guise, Christopher P., et al.
Publicado: (2014)

Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma
por: Shrestha, Prabha, et al.
Publicado: (2017)

Correction: Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor
por: Fukushima, Suguru, et al.
Publicado: (2018)

Insulin-like Growth Factor and its Therapeutic Potential for Diabetes Complications - Mechanisms and Metabolic Links: A Review
por: Biadgo, Belete, et al.
Publicado: (2021)

The Growth Factors: Potential Biomarkers and Therapeutic Targets in Kidney Diseases
por: Tang, Wei, et al.
Publicado: (2022)

Metabolic Alterations of Thyroid Cancer as Potential Therapeutic Targets
por: Ciavardelli, Domenico, et al.
Publicado: (2017)

Cancer Stem Cell Metabolism and Potential Therapeutic Targets
por: Snyder, Vusala, et al.
Publicado: (2018)

Cholesterol Metabolism: A Potential Therapeutic Target in Glioblastoma
por: Ahmad, Fahim, et al.
Publicado: (2019)

Myostatin: a potential therapeutic target for metabolic syndrome
por: Yang, Ming, et al.
Publicado: (2023)

Novel Therapeutic Targets for Hypoxia-Related Cardiovascular Diseases: The Role of HIF-1
por: Liu, Minxuan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_jrhsnfagqrdda2t3i096ok3of2