CTLA-4 blockade synergizes with cryoablation to mediate tumor rejection

We report that cryoablation of primary tumors synergizes with anti-CTLA-4 treatment to mediate rejection of secondary tumors in the TRAMP mouse model of prostate cancer. T cells, in particular CD8(+) T cells specific for the TRAMP antigen SPAS-1, were enriched in both secondary tumors and spleens of...

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Detalles Bibliográficos
Autores principales: Waitz, Rebecca, Fassò, Marcella, Allison, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382897/
https://www.ncbi.nlm.nih.gov/pubmed/22754781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382897/
https://www.ncbi.nlm.nih.gov/pubmed/22754781

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