Tumor suppressors control ULBP2, an innate surface ligand of the lymphocyte immune receptor NKG2D

The activating receptor NKG2D, expressed on different innate and adaptive cytotoxic lymphocytes, has been demonstrated to play an important role in anti-tumor immunity. Now evidence is provided that tumor suppressors control expression of its ligand ULBP2 supporting the role of this receptor-ligand...

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Detalles Bibliográficos
Autores principales: Heinemann, Anja, Paschen, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382901/
https://www.ncbi.nlm.nih.gov/pubmed/22754777
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author Heinemann, Anja
Paschen, Annette
author_facet Heinemann, Anja
Paschen, Annette
author_sort Heinemann, Anja
collection PubMed
description The activating receptor NKG2D, expressed on different innate and adaptive cytotoxic lymphocytes, has been demonstrated to play an important role in anti-tumor immunity. Now evidence is provided that tumor suppressors control expression of its ligand ULBP2 supporting the role of this receptor-ligand system as an innate barrier against tumor development.
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spelling pubmed-33829012012-07-01 Tumor suppressors control ULBP2, an innate surface ligand of the lymphocyte immune receptor NKG2D Heinemann, Anja Paschen, Annette Oncoimmunology Author's View The activating receptor NKG2D, expressed on different innate and adaptive cytotoxic lymphocytes, has been demonstrated to play an important role in anti-tumor immunity. Now evidence is provided that tumor suppressors control expression of its ligand ULBP2 supporting the role of this receptor-ligand system as an innate barrier against tumor development. Landes Bioscience 2012-07-01 /pmc/articles/PMC3382901/ /pubmed/22754777 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Heinemann, Anja
Paschen, Annette
Tumor suppressors control ULBP2, an innate surface ligand of the lymphocyte immune receptor NKG2D
title Tumor suppressors control ULBP2, an innate surface ligand of the lymphocyte immune receptor NKG2D
title_full Tumor suppressors control ULBP2, an innate surface ligand of the lymphocyte immune receptor NKG2D
title_fullStr Tumor suppressors control ULBP2, an innate surface ligand of the lymphocyte immune receptor NKG2D
title_full_unstemmed Tumor suppressors control ULBP2, an innate surface ligand of the lymphocyte immune receptor NKG2D
title_short Tumor suppressors control ULBP2, an innate surface ligand of the lymphocyte immune receptor NKG2D
title_sort tumor suppressors control ulbp2, an innate surface ligand of the lymphocyte immune receptor nkg2d
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382901/
https://www.ncbi.nlm.nih.gov/pubmed/22754777
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