Interleukin 21 impairs tumor immunosurveillance of colitis-associated colorectal cancer

The pathogenesis of colitis-associated colorectal cancer is strongly influenced by immune cells, cytokines and other immune mediators present in the inflamed colon. Current research has emerged that T helper cell associated cytokines play a prominent role in tumor growth. In our recent manuscript we...

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Detalles Bibliográficos
Autores principales: Kesselring, Rebecca, Jauch, Dominik, Fichtner-Feigl, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382907/
https://www.ncbi.nlm.nih.gov/pubmed/22754778
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author Kesselring, Rebecca
Jauch, Dominik
Fichtner-Feigl, Stefan
author_facet Kesselring, Rebecca
Jauch, Dominik
Fichtner-Feigl, Stefan
author_sort Kesselring, Rebecca
collection PubMed
description The pathogenesis of colitis-associated colorectal cancer is strongly influenced by immune cells, cytokines and other immune mediators present in the inflamed colon. Current research has emerged that T helper cell associated cytokines play a prominent role in tumor growth. In our recent manuscript we have revealed that the Th17 associated cytokine IL-21 prominently influences tumor development and immunosurveillance of colitis-associated colorectal cancer.
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spelling pubmed-33829072012-07-01 Interleukin 21 impairs tumor immunosurveillance of colitis-associated colorectal cancer Kesselring, Rebecca Jauch, Dominik Fichtner-Feigl, Stefan Oncoimmunology Author's View The pathogenesis of colitis-associated colorectal cancer is strongly influenced by immune cells, cytokines and other immune mediators present in the inflamed colon. Current research has emerged that T helper cell associated cytokines play a prominent role in tumor growth. In our recent manuscript we have revealed that the Th17 associated cytokine IL-21 prominently influences tumor development and immunosurveillance of colitis-associated colorectal cancer. Landes Bioscience 2012-07-01 /pmc/articles/PMC3382907/ /pubmed/22754778 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Kesselring, Rebecca
Jauch, Dominik
Fichtner-Feigl, Stefan
Interleukin 21 impairs tumor immunosurveillance of colitis-associated colorectal cancer
title Interleukin 21 impairs tumor immunosurveillance of colitis-associated colorectal cancer
title_full Interleukin 21 impairs tumor immunosurveillance of colitis-associated colorectal cancer
title_fullStr Interleukin 21 impairs tumor immunosurveillance of colitis-associated colorectal cancer
title_full_unstemmed Interleukin 21 impairs tumor immunosurveillance of colitis-associated colorectal cancer
title_short Interleukin 21 impairs tumor immunosurveillance of colitis-associated colorectal cancer
title_sort interleukin 21 impairs tumor immunosurveillance of colitis-associated colorectal cancer
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382907/
https://www.ncbi.nlm.nih.gov/pubmed/22754778
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AT jauchdominik interleukin21impairstumorimmunosurveillanceofcolitisassociatedcolorectalcancer
AT fichtnerfeiglstefan interleukin21impairstumorimmunosurveillanceofcolitisassociatedcolorectalcancer

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