Colon cancer cells produce immunoregulatory glucocorticoids

Expression or release of immunosuppressive molecules may protect tumor cells from the recognition and destruction by the immune system. New findings indicate that colorectal tumors produce immunoregulatory glucocorticoids and thereby suppress immune cell activation. The nuclear receptor LRH-1 plays...

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Autores principales: Sidler, Daniel, Renzulli, Pietro, Schnoz, Christina, Berger, Barbara, Schneider-Jakob, Sabine, Flück, Christa, Inderbitzin, Daniel, Corazza, Nadia, Candinas, Daniel, Brunner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382911/
https://www.ncbi.nlm.nih.gov/pubmed/22754774
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author Sidler, Daniel
Renzulli, Pietro
Schnoz, Christina
Berger, Barbara
Schneider-Jakob, Sabine
Flück, Christa
Inderbitzin, Daniel
Corazza, Nadia
Candinas, Daniel
Brunner, Thomas
author_facet Sidler, Daniel
Renzulli, Pietro
Schnoz, Christina
Berger, Barbara
Schneider-Jakob, Sabine
Flück, Christa
Inderbitzin, Daniel
Corazza, Nadia
Candinas, Daniel
Brunner, Thomas
author_sort Sidler, Daniel
collection PubMed
description Expression or release of immunosuppressive molecules may protect tumor cells from the recognition and destruction by the immune system. New findings indicate that colorectal tumors produce immunoregulatory glucocorticoids and thereby suppress immune cell activation. The nuclear receptor LRH-1 plays a critical role in the regulation of colorectal tumor proliferation and glucocorticoid synthesis.
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spelling pubmed-33829112012-07-01 Colon cancer cells produce immunoregulatory glucocorticoids Sidler, Daniel Renzulli, Pietro Schnoz, Christina Berger, Barbara Schneider-Jakob, Sabine Flück, Christa Inderbitzin, Daniel Corazza, Nadia Candinas, Daniel Brunner, Thomas Oncoimmunology Author's View Expression or release of immunosuppressive molecules may protect tumor cells from the recognition and destruction by the immune system. New findings indicate that colorectal tumors produce immunoregulatory glucocorticoids and thereby suppress immune cell activation. The nuclear receptor LRH-1 plays a critical role in the regulation of colorectal tumor proliferation and glucocorticoid synthesis. Landes Bioscience 2012-07-01 /pmc/articles/PMC3382911/ /pubmed/22754774 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Sidler, Daniel
Renzulli, Pietro
Schnoz, Christina
Berger, Barbara
Schneider-Jakob, Sabine
Flück, Christa
Inderbitzin, Daniel
Corazza, Nadia
Candinas, Daniel
Brunner, Thomas
Colon cancer cells produce immunoregulatory glucocorticoids
title Colon cancer cells produce immunoregulatory glucocorticoids
title_full Colon cancer cells produce immunoregulatory glucocorticoids
title_fullStr Colon cancer cells produce immunoregulatory glucocorticoids
title_full_unstemmed Colon cancer cells produce immunoregulatory glucocorticoids
title_short Colon cancer cells produce immunoregulatory glucocorticoids
title_sort colon cancer cells produce immunoregulatory glucocorticoids
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382911/
https://www.ncbi.nlm.nih.gov/pubmed/22754774
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