Repeated injection of PEGylated solid lipid nanoparticles induces accelerated blood clearance in mice and beagles

Surface modification of nanocarriers with amphiphilic polymer polyethylene glycol (PEG), known as PEGylation, is regarded as a major breakthrough in the application of nanocarriers. However, PEGylated nanocarriers (including liposomes and polymeric nanoparticles) induce what is referred to as the “a...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yongxue, Wang, Long, Yan, Mina, Ma, Yanling, Zang, Guangxi, She, Zhennan, Deng, Yihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383289/
https://www.ncbi.nlm.nih.gov/pubmed/22745552
http://dx.doi.org/10.2147/IJN.S30943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383289/
https://www.ncbi.nlm.nih.gov/pubmed/22745552
http://dx.doi.org/10.2147/IJN.S30943

Ejemplares similares