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Repeated injection of PEGylated solid lipid nanoparticles induces accelerated blood clearance in mice and beagles
Surface modification of nanocarriers with amphiphilic polymer polyethylene glycol (PEG), known as PEGylation, is regarded as a major breakthrough in the application of nanocarriers. However, PEGylated nanocarriers (including liposomes and polymeric nanoparticles) induce what is referred to as the “a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383289/ https://www.ncbi.nlm.nih.gov/pubmed/22745552 http://dx.doi.org/10.2147/IJN.S30943 |