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Visual Distraction: An Altered Aiming Spatial Response in Dementia
BACKGROUND/AIMS: Healthy individuals demonstrate leftward bias on visuospatial tasks such as line bisection, which has been attributed to right brain dominance. We investigated whether this asymmetry occurred in patients with probable dementia of the Alzheimer type (pAD) which is associated with neu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383303/ https://www.ncbi.nlm.nih.gov/pubmed/22739431 http://dx.doi.org/10.1159/000338571 |
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author | Galletta, Elizabeth E. Lequerica, Anthony H. Pekrul, Scott R. Eslinger, Paul J. Barrett, Anna M. |
author_facet | Galletta, Elizabeth E. Lequerica, Anthony H. Pekrul, Scott R. Eslinger, Paul J. Barrett, Anna M. |
author_sort | Galletta, Elizabeth E. |
collection | PubMed |
description | BACKGROUND/AIMS: Healthy individuals demonstrate leftward bias on visuospatial tasks such as line bisection, which has been attributed to right brain dominance. We investigated whether this asymmetry occurred in patients with probable dementia of the Alzheimer type (pAD) which is associated with neurodegenerative changes affecting temporoparietal regions. METHODS: Subjects with pAD and matched controls performed a line bisection task in near and far space under conditions of no distraction, left-sided visual distraction and right-sided visual distraction. RESULTS: Participants with pAD manifested different motor-preparatory ‘aiming’ spatial bias than matched controls. There were significantly greater rightward ‘aiming’ motor-intentional errors both without distraction and with right-sided distraction. CONCLUSION: ‘Aiming’ motor-preparatory brain activity may be induced by distraction in pAD subjects as compared to typical visual-motor function in controls. |
format | Online Article Text |
id | pubmed-3383303 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-33833032012-06-27 Visual Distraction: An Altered Aiming Spatial Response in Dementia Galletta, Elizabeth E. Lequerica, Anthony H. Pekrul, Scott R. Eslinger, Paul J. Barrett, Anna M. Dement Geriatr Cogn Dis Extra Original Research Article BACKGROUND/AIMS: Healthy individuals demonstrate leftward bias on visuospatial tasks such as line bisection, which has been attributed to right brain dominance. We investigated whether this asymmetry occurred in patients with probable dementia of the Alzheimer type (pAD) which is associated with neurodegenerative changes affecting temporoparietal regions. METHODS: Subjects with pAD and matched controls performed a line bisection task in near and far space under conditions of no distraction, left-sided visual distraction and right-sided visual distraction. RESULTS: Participants with pAD manifested different motor-preparatory ‘aiming’ spatial bias than matched controls. There were significantly greater rightward ‘aiming’ motor-intentional errors both without distraction and with right-sided distraction. CONCLUSION: ‘Aiming’ motor-preparatory brain activity may be induced by distraction in pAD subjects as compared to typical visual-motor function in controls. S. Karger AG 2012-06-13 /pmc/articles/PMC3383303/ /pubmed/22739431 http://dx.doi.org/10.1159/000338571 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Original Research Article Galletta, Elizabeth E. Lequerica, Anthony H. Pekrul, Scott R. Eslinger, Paul J. Barrett, Anna M. Visual Distraction: An Altered Aiming Spatial Response in Dementia |
title | Visual Distraction: An Altered Aiming Spatial Response in Dementia |
title_full | Visual Distraction: An Altered Aiming Spatial Response in Dementia |
title_fullStr | Visual Distraction: An Altered Aiming Spatial Response in Dementia |
title_full_unstemmed | Visual Distraction: An Altered Aiming Spatial Response in Dementia |
title_short | Visual Distraction: An Altered Aiming Spatial Response in Dementia |
title_sort | visual distraction: an altered aiming spatial response in dementia |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383303/ https://www.ncbi.nlm.nih.gov/pubmed/22739431 http://dx.doi.org/10.1159/000338571 |
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