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Visual Distraction: An Altered Aiming Spatial Response in Dementia

BACKGROUND/AIMS: Healthy individuals demonstrate leftward bias on visuospatial tasks such as line bisection, which has been attributed to right brain dominance. We investigated whether this asymmetry occurred in patients with probable dementia of the Alzheimer type (pAD) which is associated with neu...

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Autores principales: Galletta, Elizabeth E., Lequerica, Anthony H., Pekrul, Scott R., Eslinger, Paul J., Barrett, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383303/
https://www.ncbi.nlm.nih.gov/pubmed/22739431
http://dx.doi.org/10.1159/000338571
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author Galletta, Elizabeth E.
Lequerica, Anthony H.
Pekrul, Scott R.
Eslinger, Paul J.
Barrett, Anna M.
author_facet Galletta, Elizabeth E.
Lequerica, Anthony H.
Pekrul, Scott R.
Eslinger, Paul J.
Barrett, Anna M.
author_sort Galletta, Elizabeth E.
collection PubMed
description BACKGROUND/AIMS: Healthy individuals demonstrate leftward bias on visuospatial tasks such as line bisection, which has been attributed to right brain dominance. We investigated whether this asymmetry occurred in patients with probable dementia of the Alzheimer type (pAD) which is associated with neurodegenerative changes affecting temporoparietal regions. METHODS: Subjects with pAD and matched controls performed a line bisection task in near and far space under conditions of no distraction, left-sided visual distraction and right-sided visual distraction. RESULTS: Participants with pAD manifested different motor-preparatory ‘aiming’ spatial bias than matched controls. There were significantly greater rightward ‘aiming’ motor-intentional errors both without distraction and with right-sided distraction. CONCLUSION: ‘Aiming’ motor-preparatory brain activity may be induced by distraction in pAD subjects as compared to typical visual-motor function in controls.
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spelling pubmed-33833032012-06-27 Visual Distraction: An Altered Aiming Spatial Response in Dementia Galletta, Elizabeth E. Lequerica, Anthony H. Pekrul, Scott R. Eslinger, Paul J. Barrett, Anna M. Dement Geriatr Cogn Dis Extra Original Research Article BACKGROUND/AIMS: Healthy individuals demonstrate leftward bias on visuospatial tasks such as line bisection, which has been attributed to right brain dominance. We investigated whether this asymmetry occurred in patients with probable dementia of the Alzheimer type (pAD) which is associated with neurodegenerative changes affecting temporoparietal regions. METHODS: Subjects with pAD and matched controls performed a line bisection task in near and far space under conditions of no distraction, left-sided visual distraction and right-sided visual distraction. RESULTS: Participants with pAD manifested different motor-preparatory ‘aiming’ spatial bias than matched controls. There were significantly greater rightward ‘aiming’ motor-intentional errors both without distraction and with right-sided distraction. CONCLUSION: ‘Aiming’ motor-preparatory brain activity may be induced by distraction in pAD subjects as compared to typical visual-motor function in controls. S. Karger AG 2012-06-13 /pmc/articles/PMC3383303/ /pubmed/22739431 http://dx.doi.org/10.1159/000338571 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Original Research Article
Galletta, Elizabeth E.
Lequerica, Anthony H.
Pekrul, Scott R.
Eslinger, Paul J.
Barrett, Anna M.
Visual Distraction: An Altered Aiming Spatial Response in Dementia
title Visual Distraction: An Altered Aiming Spatial Response in Dementia
title_full Visual Distraction: An Altered Aiming Spatial Response in Dementia
title_fullStr Visual Distraction: An Altered Aiming Spatial Response in Dementia
title_full_unstemmed Visual Distraction: An Altered Aiming Spatial Response in Dementia
title_short Visual Distraction: An Altered Aiming Spatial Response in Dementia
title_sort visual distraction: an altered aiming spatial response in dementia
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383303/
https://www.ncbi.nlm.nih.gov/pubmed/22739431
http://dx.doi.org/10.1159/000338571
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