Cargando…

Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy

We present a long followed up case of acute central serous chorioretinopathy (CSC) complicated by a severe visual loss due to massive pigment epithelium detachment of the macula after a full-dose photodynamic therapy (PDT). Rapid anatomical and functional improvement was observed after a single intr...

Descripción completa

Detalles Bibliográficos
Autores principales: G. Kotoula, Maria, Zacharaki, Fani, E. Tsironi, Evangelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383330/
https://www.ncbi.nlm.nih.gov/pubmed/22740830
http://dx.doi.org/10.1159/000339656
_version_ 1782236609498841088
author G. Kotoula, Maria
Zacharaki, Fani
E. Tsironi, Evangelia
author_facet G. Kotoula, Maria
Zacharaki, Fani
E. Tsironi, Evangelia
author_sort G. Kotoula, Maria
collection PubMed
description We present a long followed up case of acute central serous chorioretinopathy (CSC) complicated by a severe visual loss due to massive pigment epithelium detachment of the macula after a full-dose photodynamic therapy (PDT). Rapid anatomical and functional improvement was observed after a single intravitreal injection of bevacizumab. To our knowledge, we report the first case of PDT-treated CSC complicated by severe visual loss. We can only speculate that the serous detachment of the posterior pole might have been caused by PDT-induced VEGF overexpression, explaining such an impressive response to Avastin treatment.
format Online
Article
Text
id pubmed-3383330
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher S. Karger AG
record_format MEDLINE/PubMed
spelling pubmed-33833302012-06-27 Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy G. Kotoula, Maria Zacharaki, Fani E. Tsironi, Evangelia Case Rep Ophthalmol Published online: June, 2012 We present a long followed up case of acute central serous chorioretinopathy (CSC) complicated by a severe visual loss due to massive pigment epithelium detachment of the macula after a full-dose photodynamic therapy (PDT). Rapid anatomical and functional improvement was observed after a single intravitreal injection of bevacizumab. To our knowledge, we report the first case of PDT-treated CSC complicated by severe visual loss. We can only speculate that the serous detachment of the posterior pole might have been caused by PDT-induced VEGF overexpression, explaining such an impressive response to Avastin treatment. S. Karger AG 2012-06-12 /pmc/articles/PMC3383330/ /pubmed/22740830 http://dx.doi.org/10.1159/000339656 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: June, 2012
G. Kotoula, Maria
Zacharaki, Fani
E. Tsironi, Evangelia
Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy
title Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy
title_full Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy
title_fullStr Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy
title_full_unstemmed Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy
title_short Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy
title_sort intravitreal bevacizumab for photodynamic therapy-induced massive macular detachment in acute central serous chorioretinopathy
topic Published online: June, 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383330/
https://www.ncbi.nlm.nih.gov/pubmed/22740830
http://dx.doi.org/10.1159/000339656
work_keys_str_mv AT gkotoulamaria intravitrealbevacizumabforphotodynamictherapyinducedmassivemaculardetachmentinacutecentralserouschorioretinopathy
AT zacharakifani intravitrealbevacizumabforphotodynamictherapyinducedmassivemaculardetachmentinacutecentralserouschorioretinopathy
AT etsironievangelia intravitrealbevacizumabforphotodynamictherapyinducedmassivemaculardetachmentinacutecentralserouschorioretinopathy