Protein interactions with piALU RNA indicates putative participation of retroRNA in the cell cycle, DNA repair and chromatin assembly

Recent analyses suggest that transposable element-derived transcripts are processed to yield a variety of small RNA species that play critical functional roles in gene regulation and chromatin organization as well as genome stability and maintenance. Here we report a mass spectrometry analysis of an...

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Autores principales: Blackwell, Benjamin J., Lopez, Mary F., Wang, Jianrong, Krastins, Bryan, Sarracino, David, Tollervey, James R., Dobke, Marek, Jordan, I. King, Lunyak, Victoria V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383447/
https://www.ncbi.nlm.nih.gov/pubmed/22754750
http://dx.doi.org/10.4161/mge.19032
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author Blackwell, Benjamin J.
Lopez, Mary F.
Wang, Jianrong
Krastins, Bryan
Sarracino, David
Tollervey, James R.
Dobke, Marek
Jordan, I. King
Lunyak, Victoria V.
author_facet Blackwell, Benjamin J.
Lopez, Mary F.
Wang, Jianrong
Krastins, Bryan
Sarracino, David
Tollervey, James R.
Dobke, Marek
Jordan, I. King
Lunyak, Victoria V.
author_sort Blackwell, Benjamin J.
collection PubMed
description Recent analyses suggest that transposable element-derived transcripts are processed to yield a variety of small RNA species that play critical functional roles in gene regulation and chromatin organization as well as genome stability and maintenance. Here we report a mass spectrometry analysis of an RNA-affinity complex isolation using a piRNA homologous sequence derived from Alu retrotransposal RNA. Our data point to potential roles for piALU RNAs in DNA repair, cell cycle and chromatin regulations.
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spelling pubmed-33834472012-06-29 Protein interactions with piALU RNA indicates putative participation of retroRNA in the cell cycle, DNA repair and chromatin assembly Blackwell, Benjamin J. Lopez, Mary F. Wang, Jianrong Krastins, Bryan Sarracino, David Tollervey, James R. Dobke, Marek Jordan, I. King Lunyak, Victoria V. Mob Genet Elements Research Paper Recent analyses suggest that transposable element-derived transcripts are processed to yield a variety of small RNA species that play critical functional roles in gene regulation and chromatin organization as well as genome stability and maintenance. Here we report a mass spectrometry analysis of an RNA-affinity complex isolation using a piRNA homologous sequence derived from Alu retrotransposal RNA. Our data point to potential roles for piALU RNAs in DNA repair, cell cycle and chromatin regulations. Landes Bioscience 2012-01-01 /pmc/articles/PMC3383447/ /pubmed/22754750 http://dx.doi.org/10.4161/mge.19032 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Research Paper
Blackwell, Benjamin J.
Lopez, Mary F.
Wang, Jianrong
Krastins, Bryan
Sarracino, David
Tollervey, James R.
Dobke, Marek
Jordan, I. King
Lunyak, Victoria V.
Protein interactions with piALU RNA indicates putative participation of retroRNA in the cell cycle, DNA repair and chromatin assembly
title Protein interactions with piALU RNA indicates putative participation of retroRNA in the cell cycle, DNA repair and chromatin assembly
title_full Protein interactions with piALU RNA indicates putative participation of retroRNA in the cell cycle, DNA repair and chromatin assembly
title_fullStr Protein interactions with piALU RNA indicates putative participation of retroRNA in the cell cycle, DNA repair and chromatin assembly
title_full_unstemmed Protein interactions with piALU RNA indicates putative participation of retroRNA in the cell cycle, DNA repair and chromatin assembly
title_short Protein interactions with piALU RNA indicates putative participation of retroRNA in the cell cycle, DNA repair and chromatin assembly
title_sort protein interactions with pialu rna indicates putative participation of retrorna in the cell cycle, dna repair and chromatin assembly
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383447/
https://www.ncbi.nlm.nih.gov/pubmed/22754750
http://dx.doi.org/10.4161/mge.19032
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