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Molecular Dynamics Simulations Suggest Ligand’s Binding to Nicotinamidase/Pyrazinamidase

The research on the binding process of ligand to pyrazinamidase (PncA) is crucial for elucidating the inherent relationship between resistance of Mycobacterium tuberculosis and PncA’s activity. In the present study, molecular dynamics (MD) simulation methods were performed to investigate the unbindi...

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Detalles Bibliográficos
Autores principales:	Zhang, Ji-Long, Zheng, Qing-Chuan, Li, Zheng-Qiang, Zhang, Hong-Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383691/ https://www.ncbi.nlm.nih.gov/pubmed/22761821 http://dx.doi.org/10.1371/journal.pone.0039546

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