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Effects of Activin and TGFβ on p21 in Colon Cancer

Activin and TGFβ share SMAD signaling and colon cancers can inactivate either pathway alone or simultaneously. The differential effects of activin and TGFβ signaling in colon cancer have not been previously dissected. A key downstream target of TGFβ signaling is the cdk2 inhibitor p21 (p21(cip1/waf1...

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Detalles Bibliográficos
Autores principales:	Bauer, Jessica, Sporn, Judith C., Cabral, Jennifer, Gomez, Jessica, Jung, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383701/ https://www.ncbi.nlm.nih.gov/pubmed/22761777 http://dx.doi.org/10.1371/journal.pone.0039381

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