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Lovastatin Modulates Glycogen Synthase Kinase-3β Pathway and Inhibits Mossy Fiber Sprouting after Pilocarpine-Induced Status Epilepticus

This study was undertaken to assay the effect of lovastatin on the glycogen synthase kinase-3 beta (GSK-3β) and collapsin responsive mediator protein-2 (CRMP-2) signaling pathway and mossy fiber sprouting (MFS) in epileptic rats. MFS in the dentate gyrus (DG) is an important feature of temporal lobe...

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Detalles Bibliográficos
Autores principales:	Lee, Chun-Yao, Jaw, Thomas, Tseng, Huan-Chin, Chen, I-Chun, Liou, Horng-Huei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383707/ https://www.ncbi.nlm.nih.gov/pubmed/22761705 http://dx.doi.org/10.1371/journal.pone.0038789

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