Cargando…

The architecture of the BubR1 tetratricopeptide tandem repeat defines a protein motif underlying mitotic checkpoint-kinetochore communication

The accurate and timely transmission of the genetic material to progeny during successive rounds of cell division is sine qua non for the maintenance of genome stability. Eukaryotic cells have evolved a surveillance mechanism, the mitotic spindle assembly checkpoint (SAC), to prevent premature advan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bolanos-Garcia, Victor M., Nilsson, Jakob, Blundell, Tom L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383715/ https://www.ncbi.nlm.nih.gov/pubmed/22754625

Ejemplares similares

Characterization of Spindle Checkpoint Kinase Mps1 Reveals Domain with Functional and Structural Similarities to Tetratricopeptide Repeat Motifs of Bub1 and BubR1 Checkpoint Kinases
por: Lee, Semin, et al.
Publicado: (2012)

Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint
por: Zhang, Gang, et al.
Publicado: (2015)

Defining the Molecular Basis of BubR1 Kinetochore Interactions and APC/C-CDC20 Inhibition
por: D'Arcy, Sheena, et al.
Publicado: (2010)

Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit
por: Huang, Haomin, et al.
Publicado: (2008)

BubR1 recruitment to the kinetochore via Bub1 enhances spindle assembly checkpoint signaling
por: Banerjee, Anand, et al.
Publicado: (2022)

BUB1 and BUBR1: multifaceted kinases of the cell cycle
por: Bolanos-Garcia, Victor M., et al.
Publicado: (2011)

Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site
por: Bolanos-Garcia, Victor M., et al.
Publicado: (2011)

Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site
por: Bolanos-Garcia, Victor M., et al.
Publicado: (2011)

Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation
por: Zhang, Gang, et al.
Publicado: (2016)

Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling
por: Mao, Yinghui, et al.
Publicado: (2005)

CENP-E–dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint
por: Guo, Yige, et al.
Publicado: (2012)

Pellino 1 inactivates mitotic spindle checkpoint by targeting BubR1 for ubiquitinational degradation
por: Park, Jihyun, et al.
Publicado: (2017)

BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1
por: Chen, Rey-Huei
Publicado: (2002)

Separating the spindle, checkpoint, and timer functions of BubR1
por: Rahmani, Zohra, et al.
Publicado: (2009)

A novel mutation in the N-terminal domain of Drosophila BubR1 affects the spindle assembly checkpoint function of BubR1
por: Duranteau, Marie, et al.
Publicado: (2016)

Coupling of Cdc20 inhibition and activation by BubR1
por: Hein, Jamin B., et al.
Publicado: (2021)

Drosophila CENP-A Mutations Cause a BubR1- Dependent Early Mitotic Delay without Normal Localization of Kinetochore Components
por: Blower, Michael D, et al.
Publicado: (2006)

Overexpression of the Mitotic Checkpoint Genes BUB1 and BUBR1 is Associated with Genomic Complexity in Clear Cell Kidney Carcinomas
por: Pinto, Mafalda, et al.
Publicado: (2008)

A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint
por: Overlack, Katharina, et al.
Publicado: (2015)

BubR1 and brain aging
por: Hussaini, Syed Mohammed Qasim, et al.
Publicado: (2017)

BubR1 alterations that reinforce mitotic surveillance act against aneuploidy and cancer
por: Weaver, Robbyn L, et al.
Publicado: (2016)

BubR1 checks in with CENP-E
por: LeBrasseur, Nicole
Publicado: (2003)

BubR1 shows self-control
por: Short, Ben
Publicado: (2012)

BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling
por: Overlack, Katharina, et al.
Publicado: (2017)

Phylogenomics-guided discovery of a novel conserved cassette of short linear motifs in BubR1 essential for the spindle checkpoint
por: Tromer, Eelco, et al.
Publicado: (2016)

Human Bubr1 Is a Mitotic Checkpoint Kinase That Monitors Cenp-E Functions at Kinetochores and Binds the Cyclosome/APC
por: Chan, G.K.T., et al.
Publicado: (1999)

TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity
por: Tomasini, Richard, et al.
Publicado: (2009)

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
por: Ditchfield, Claire, et al.
Publicado: (2003)

Escaping the firing squad: acetylation of BubR1 protects it from degradation in checkpoint cells
por: Yekezare, Mona, et al.
Publicado: (2009)

Physiological relevance of post-translational regulation of the spindle assembly checkpoint protein BubR1
por: Bloom, Celia R., et al.
Publicado: (2021)

Loss of Centromere Cohesion in Aneuploid Human Oocytes Correlates with Decreased Kinetochore Localization of the Sac Proteins Bub1 and Bubr1
por: Lagirand-Cantaloube, Julie, et al.
Publicado: (2017)

The Crystal Structure of the N-Terminal Region of BUB1 Provides Insight into the Mechanism of BUB1 Recruitment to Kinetochores
por: Bolanos-Garcia, Victor M., et al.
Publicado: (2009)

Mitotic checkpoints, MUGs and kinetochores
por: Brinkley, Bill R.
Publicado: (2013)

The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases
por: Ciossani, Giuseppe, et al.
Publicado: (2018)

Loss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation
por: Park, Inai, et al.
Publicado: (2013)

The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1
por: Lee, Miyoung, et al.
Publicado: (2017)

Requirement for BUB1B/BUBR1 in tumor progression of lung adenocarcinoma
por: Chen, Honglin, et al.
Publicado: (2015)

The progeroid gene BubR1 regulates axon myelination and motor function
por: Choi, Chan-Il, et al.
Publicado: (2016)

BubR1 Insufficiency Impairs Affective Behavior and Memory Function in Mice
por: Cho, Chang Hoon, et al.
Publicado: (2018)

Age‐related decline in BubR1 impairs adult hippocampal neurogenesis
por: Yang, Zhongxi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_hvo8hbcefsmmru8nd1vmqqstav