Regulation of bi-directional movement of single kinesin-5 Cin8 molecules

Kinesin-5 mechanoenzymes drive mitotic spindle dynamics as slow, processive microtubule (MT)-plus-end directed motors. Surprisingly, the Saccharomyces cerevisiae kinesin-5 Cin8 was recently found to be bi-directional: it can move processively in both directions on MTs. Two hypotheses have been sugge...

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Detalles Bibliográficos
Autores principales: Thiede, Christina, Fridman, Vladimir, Gerson-Gurwitz, Adina, Gheber, Larisa, Schmidt, Christoph F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383724/
https://www.ncbi.nlm.nih.gov/pubmed/22754632

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