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An Autism-Associated Variant of Epac2 Reveals a Role for Ras/Epac2 Signaling in Controlling Basal Dendrite Maintenance in Mice
The architecture of dendritic arbors determines circuit connectivity, receptive fields, and computational properties of neurons, and dendritic structure is impaired in several psychiatric disorders. While apical and basal dendritic compartments of pyramidal neurons are functionally specialized and d...
Autores principales: | Srivastava, Deepak P., Woolfrey, Kevin M., Jones, Kelly A., Anderson, Charles T., Smith, Katharine R., Russell, Theron A., Lee, Hyerin, Yasvoina, Marina V., Wokosin, David L., Ozdinler, P. Hande, Shepherd, Gordon M. G., Penzes, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383751/ https://www.ncbi.nlm.nih.gov/pubmed/22745599 http://dx.doi.org/10.1371/journal.pbio.1001350 |
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