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Effects of the Insemination of Hydrogen Peroxide-Treated Epididymal Mouse Spermatozoa on γH2AX Repair and Embryo Development

BACKGROUND: Cryopreservation of human semen for assisted reproduction is complicated by cryodamage to spermatozoa caused by excessive reactive oxygen species (ROS) generation. METHODS AND FINDINGS: We used exogenous ROS (H(2)O(2)) to simulate cryopreservation and examined DNA damage repair in embryo...

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Detalles Bibliográficos
Autores principales:	Xiao, Jianfeng, Liu, Yanmei, Li, Zhiling, Zhou, Yongcui, Lin, Hong, Wu, Xiaoyan, Chen, Man, Xiao, Wanfen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383764/ https://www.ncbi.nlm.nih.gov/pubmed/22745678 http://dx.doi.org/10.1371/journal.pone.0038742

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