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Hfe Deficiency Impairs Pulmonary Neutrophil Recruitment in Response to Inflammation

Regulation of iron homeostasis and the inflammatory response are tightly linked to protect the host from infection. Here we investigate how imbalanced systemic iron homeostasis in a murine disease model of hereditary hemochromatosis (Hfe(−/−) mice) affects the inflammatory responses of the lung. We...

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Detalles Bibliográficos
Autores principales: Benesova, Karolina, Vujić Spasić, Maja, Schaefer, Sebastian M., Stolte, Jens, Baehr-Ivacevic, Tomi, Waldow, Katharina, Zhou, Zhe, Klingmueller, Ursula, Benes, Vladimir, Mall, Marcus A., Muckenthaler, Martina U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383765/
https://www.ncbi.nlm.nih.gov/pubmed/22745741
http://dx.doi.org/10.1371/journal.pone.0039363