Cargando…
Hfe Deficiency Impairs Pulmonary Neutrophil Recruitment in Response to Inflammation
Regulation of iron homeostasis and the inflammatory response are tightly linked to protect the host from infection. Here we investigate how imbalanced systemic iron homeostasis in a murine disease model of hereditary hemochromatosis (Hfe(−/−) mice) affects the inflammatory responses of the lung. We...
Autores principales: | Benesova, Karolina, Vujić Spasić, Maja, Schaefer, Sebastian M., Stolte, Jens, Baehr-Ivacevic, Tomi, Waldow, Katharina, Zhou, Zhe, Klingmueller, Ursula, Benes, Vladimir, Mall, Marcus A., Muckenthaler, Martina U. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383765/ https://www.ncbi.nlm.nih.gov/pubmed/22745741 http://dx.doi.org/10.1371/journal.pone.0039363 |
Ejemplares similares
-
Macrophage-HFE controls iron metabolism and immune responses in aged mice
por: Tangudu, Naveen Kumar, et al.
Publicado: (2020) -
Molecular basis of HFE-hemochromatosis
por: Vujić, Maja
Publicado: (2014) -
Lymphocyte Gene Expression Signatures from Patients and Mouse Models of Hereditary Hemochromatosis Reveal a Function of HFE as a Negative Regulator of CD8(+) T-Lymphocyte Activation and Differentiation In Vivo
por: Costa, Mónica, et al.
Publicado: (2015) -
Hfe Actions in Kupffer Cells Are Dispensable for Hepatic and Systemic Iron Metabolism
por: Knoop, Paul, et al.
Publicado: (2023) -
Thyrotroph Embryonic Factor Regulates Light-Induced Transcription of Repair Genes in Zebrafish Embryonic Cells
por: Gavriouchkina, Daria, et al.
Publicado: (2010)