The FAT10- and ubiquitin-dependent degradation machineries exhibit common and distinct requirements for MHC class I antigen presentation

Like ubiquitin (Ub), the ubiquitin-like protein FAT10 can serve as a signal for proteasome-dependent protein degradation. Here, we investigated the contribution of FAT10 substrate modification to MHC class I antigen presentation. We show that N-terminal modification of the human cytomegalovirus-deri...

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Detalles Bibliográficos
Autores principales: Ebstein, Frédéric, Lehmann, Andrea, Kloetzel, Peter-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383951/
https://www.ncbi.nlm.nih.gov/pubmed/22349260
http://dx.doi.org/10.1007/s00018-012-0933-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383951/
https://www.ncbi.nlm.nih.gov/pubmed/22349260
http://dx.doi.org/10.1007/s00018-012-0933-5

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