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LINE-1 hypomethylation in familial and sporadic cancer

Increased and decreased methylation at specific sequences (hypermethylation and hypomethylation, respectively) is characteristic of tumor DNA compared to normal DNA and promotes carcinogenesis in multiple ways including genomic instability. Long interspersed element (LINE), an abundant class of retr...

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Detalles Bibliográficos
Autores principales:	Pavicic, Walter, Joensuu, Emmi I., Nieminen, Taina, Peltomäki, Päivi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383956/ https://www.ncbi.nlm.nih.gov/pubmed/22228215 http://dx.doi.org/10.1007/s00109-011-0854-z

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