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Neutrophil Infiltration of the Colon Is Independent of the FPR1 yet FPR1 Deficient Mice Show Differential Susceptibilities to Acute Versus Chronic Induced Colitis

BACKGROUND: The receptor for formylated peptides, formyl peptide receptor 1 (FPR1), potently activates and serves as a chemoattractant receptor for neutrophils. AIM: Given the abundance of neutrophils in the inflamed colon, our aim was to determine if the FPR1 mediates colonic neutrophil migration,...

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Detalles Bibliográficos
Autores principales: Farooq, Shukkur M., Stadnyk, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383957/
https://www.ncbi.nlm.nih.gov/pubmed/22383080
http://dx.doi.org/10.1007/s10620-012-2082-y