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Effects of dietary inulin, statin, and their co-treatment on hyperlipidemia, hepatic steatosis and changes in drug-metabolizing enzymes in rats fed a high-fat and high-sucrose diet
BACKGROUND: Rats fed a high-fat and high-sucrose (HF) diet develop hepatic steatosis and hyperlipidemia. There are several reports that a change in nutritional status affects hepatic levels of drug-metabolizing enzymes. Synthetic inulin is a dietary component that completely evades glucide digestion...
Autores principales: | Sugatani, Junko, Sadamitsu, Satoshi, Wada, Tadashi, Yamazaki, Yasuhiro, Ikari, Akira, Miwa, Masao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384239/ https://www.ncbi.nlm.nih.gov/pubmed/22452877 http://dx.doi.org/10.1186/1743-7075-9-23 |
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