CTCF binds to sites in the major histocompatibility complex that are rapidly reconfigured in response to interferon-gamma

Activation of the major histocompatibility complex (MHC) by interferon-gamma (IFN−γ) is a fundamental step in the adaptive immune response to pathogens. Here, we show that reorganization of chromatin loop domains in the MHC is evident within the first 30 min of IFN−γ treatment of fibroblasts, and th...

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Detalles Bibliográficos
Autores principales: Ottaviani, Diego, Lever, Elliott, Mao, Shihong, Christova, Rossitza, Ogunkolade, Babatunji W., Jones, Tania A., Szary, Jaroslaw, Aarum, Johan, Mumin, Muhammad A., Pieri, Christopher A., Krawetz, Stephen A., Sheer, Denise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384298/
https://www.ncbi.nlm.nih.gov/pubmed/22367884
http://dx.doi.org/10.1093/nar/gks158

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