Cargando…

Regulation of AT1R expression through HuR by insulin

Angiotensin II type 1 receptor (AT1R) has a pathophysiological role in hypertension, atherosclerosis and heart failure. Type 2 diabetes is hyperinsulinemic state and a major risk factor for atherosclerosis and hypertension. It is known that hyperinsulinemia upregulates AT1R expression post-transcrip...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paukku, Kirsi, Backlund, Michael, De Boer, Rudolf A., Kalkkinen, Nisse, Kontula, Kimmo K., Lehtonen, Jukka Y. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384301/ https://www.ncbi.nlm.nih.gov/pubmed/22362742 http://dx.doi.org/10.1093/nar/gks170

Ejemplares similares

Endoplasmic reticulum stress increases AT1R mRNA expression via TIA-1-dependent mechanism
por: Backlund, Michael, et al.
Publicado: (2016)

Posttranscriptional regulation of angiotensin II type 1 receptor expression by glyceraldehyde 3-phosphate dehydrogenase
por: Backlund, Michael, et al.
Publicado: (2009)

p100 increases AT1R expression through interaction with AT1R 3′-UTR
por: Paukku, Kirsi, et al.
Publicado: (2008)

Post-transcriptional regulation of Pabpn1 by the RNA binding protein HuR
por: Phillips, Brittany L, et al.
Publicado: (2018)

RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability
por: Cho, Seong Jun, et al.
Publicado: (2010)

Heterogeneous ribonucleoprotein C displays a repressor activity mediated by T-cell intracellular antigen-1-related/like protein to modulate Fas exon 6 splicing through a mechanism involving Hu antigen R
por: Izquierdo, José M.
Publicado: (2010)

Functional and direct interaction between the RNA binding protein HuD and active Akt1
por: Fujiwara, Toshinobu, et al.
Publicado: (2012)

The activity of CouR, a MarR family transcriptional regulator, is modulated through a novel molecular mechanism
por: Otani, Hiroshi, et al.
Publicado: (2016)

Impaired function of rDNA transcription initiation machinery leads to derepression of ribosomal genes with insertions of R2 retrotransposon
por: Fefelova, Elena A, et al.
Publicado: (2022)

Comprehensive insights into Mycobacterium tuberculosis DevR (DosR) regulon activation switch
por: Chauhan, Santosh, et al.
Publicado: (2011)

Enhanced binding of an HU homologue under increased DNA supercoiling preserves chromosome organisation and sustains Streptomyces hyphal growth
por: Strzałka, Agnieszka, et al.
Publicado: (2022)

Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRγ
por: Song, Guisheng, et al.
Publicado: (2008)

Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells
por: Baselga-Escudero, Laura, et al.
Publicado: (2014)

The PurR regulon in Escherichia coli K-12 MG1655
por: Cho, Byung-Kwan, et al.
Publicado: (2011)

Myc-induced anchorage of the rDNA IGS region to nucleolar matrix modulates growth-stimulated changes in higher-order rDNA architecture
por: Shiue, Chiou-Nan, et al.
Publicado: (2014)

ChIP-seq analysis of the LuxR-type regulator VjbR reveals novel insights into the Brucella virulence gene expression network
por: Kleinman, Claudia L., et al.
Publicado: (2017)

Linc-RoR promotes c-Myc expression through hnRNP I and AUF1
por: Huang, Jianguo, et al.
Publicado: (2016)

Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR
por: Castellano, Leandro, et al.
Publicado: (2017)

Unscheduled epigenetic modifications cause genome instability and sterility through aberrant R-loops following starvation
por: Sun, Bing, et al.
Publicado: (2022)

Characterization of a cAMP responsive transcription factor, Cmr (Rv1675c), in TB complex mycobacteria reveals overlap with the DosR (DevR) dormancy regulon
por: Ranganathan, Sridevi, et al.
Publicado: (2016)

Twist-1 regulates the miR-199a/214 cluster during development
por: Lee, Youn-Bok, et al.
Publicado: (2009)

DNA sequence encoded repression of rRNA gene transcription in chromatin
por: Felle, Max, et al.
Publicado: (2010)

miR-34 is maternally inherited in Drosophila melanogaster and Danio rerio
por: Soni, Kartik, et al.
Publicado: (2013)

The architecture of ArgR-DNA complexes at the genome-scale in Escherichia coli
por: Cho, Suhyung, et al.
Publicado: (2015)

Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops
por: Ma, Tiffany S, et al.
Publicado: (2023)

Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos
por: Yeung, Fan, et al.
Publicado: (2012)

Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion
por: Yang, Xiangling, et al.
Publicado: (2013)

Global regulation of gene expression by OxyR in an important human opportunistic pathogen
por: Wei, Qing, et al.
Publicado: (2012)

Non-inhibited miRNAs shape the cellular response to anti-miR
por: Androsavich, John R., et al.
Publicado: (2014)

MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma
por: Lodrini, Marco, et al.
Publicado: (2013)

MouR controls the expression of the Listeria monocytogenes Agr system and mediates virulence
por: Pinheiro, Jorge, et al.
Publicado: (2018)

TDRD3 promotes DHX9 chromatin recruitment and R-loop resolution
por: Yuan, Wei, et al.
Publicado: (2021)

Live-cell imaging unveils distinct R-loop populations with heterogeneous dynamics
por: Martin, Robert M, et al.
Publicado: (2023)

Glucose depletion activates mmu-miR-466h-5p expression through oxidative stress and inhibition of histone deacetylation
por: Druz, Aliaksandr, et al.
Publicado: (2012)

macroH2A1 histone variant represses rDNA transcription
por: Cong, Rong, et al.
Publicado: (2014)

Genome-wide relationship between R-loop formation and antisense transcription in Escherichia coli
por: Raghunathan, Nalini, et al.
Publicado: (2018)

Regulation of miR-34b/c-targeted gene expression program by SUMOylation
por: Li, Yi-Jia, et al.
Publicado: (2018)

QstR-dependent regulation of natural competence and type VI secretion in Vibrio cholerae
por: Jaskólska, Milena, et al.
Publicado: (2018)

Characterization of the pleiotropic LysR-type transcription regulator LeuO of Escherichia coli
por: Fragel, Susann M, et al.
Publicado: (2019)

Facultative heterochromatin formation in rDNA is essential for cell survival during nutritional starvation
por: Hirai, Hayato, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hggjvmug5j8tvtkak3o7ps5if3