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Structural and functional characterization of interactions involving the Tfb1 subunit of TFIIH and the NER factor Rad2

The general transcription factor IIH (TFIIH) plays crucial roles in transcription as part of the pre-initiation complex (PIC) and in DNA repair as part of the nucleotide excision repair (NER) machinery. During NER, TFIIH recruits the 3′-endonuclease Rad2 to damaged DNA. In this manuscript, we functi...

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Detalles Bibliográficos
Autores principales:	Lafrance-Vanasse, Julien, Arseneault, Geneviève, Cappadocia, Laurent, Chen, Hung-Ta, Legault, Pascale, Omichinski, James G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384317/ https://www.ncbi.nlm.nih.gov/pubmed/22373916 http://dx.doi.org/10.1093/nar/gks194

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