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HnRNP L and L-like cooperate in multiple-exon regulation of CD45 alternative splicing

CD45 encodes a trans-membrane protein-tyrosine phosphatase expressed in diverse cells of the immune system. By combinatorial use of three variable exons 4–6, isoforms are generated that differ in their extracellular domain, thereby modulating phosphatase activity and immune response. Alternative spl...

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Detalles Bibliográficos
Autores principales:	Preußner, Marco, Schreiner, Silke, Hung, Lee-Hsueh, Porstner, Martina, Jäck, Hans-Martin, Benes, Vladimir, Rätsch, Gunnar, Bindereif, Albrecht
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384337/ https://www.ncbi.nlm.nih.gov/pubmed/22402488 http://dx.doi.org/10.1093/nar/gks221

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