Arp2/3 complex–dependent actin networks constrain myosin II function in driving retrograde actin flow

The Arp2/3 complex nucleates actin filaments to generate networks at the leading edge of motile cells. Nonmuscle myosin II produces contractile forces involved in driving actin network translocation. We inhibited the Arp2/3 complex and/or myosin II with small molecules to investigate their respectiv...

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Detalles Bibliográficos
Autores principales: Yang, Qing, Zhang, Xiao-Feng, Pollard, Thomas D., Forscher, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384413/
https://www.ncbi.nlm.nih.gov/pubmed/22711700
http://dx.doi.org/10.1083/jcb.201111052

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