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Kar3Vik1, a member of the Kinesin-14 superfamily, shows a novel kinesin microtubule binding pattern

Kinesin-14 motors generate microtubule minus-end–directed force used in mitosis and meiosis. These motors are dimeric and operate with a nonprocessive powerstroke mechanism, but the role of the second head in motility has been unclear. In Saccharomyces cerevisiae, the Kinesin-14 Kar3 forms a heterod...

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Detalles Bibliográficos
Autores principales: Rank, Katherine C., Chen, Chun Ju, Cope, Julia, Porche, Ken, Hoenger, Andreas, Gilbert, Susan P., Rayment, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384419/
https://www.ncbi.nlm.nih.gov/pubmed/22734002
http://dx.doi.org/10.1083/jcb.201201132