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Kar3Vik1, a member of the Kinesin-14 superfamily, shows a novel kinesin microtubule binding pattern
Kinesin-14 motors generate microtubule minus-end–directed force used in mitosis and meiosis. These motors are dimeric and operate with a nonprocessive powerstroke mechanism, but the role of the second head in motility has been unclear. In Saccharomyces cerevisiae, the Kinesin-14 Kar3 forms a heterod...
Autores principales: | Rank, Katherine C., Chen, Chun Ju, Cope, Julia, Porche, Ken, Hoenger, Andreas, Gilbert, Susan P., Rayment, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384419/ https://www.ncbi.nlm.nih.gov/pubmed/22734002 http://dx.doi.org/10.1083/jcb.201201132 |
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