Integrin α5β1 simultaneously controls EGFR-dependent proliferation and Akt-dependent pro-survival signaling in epidermoid carcinoma cells

To delineate distinctive role of the components of α5β1 integrin-EGFR axis in control of epidermoid carcinoma cell proliferation, we performed individual inhibition of α5β1 and EGFR via genetic and phamacological methods, respectively. We demonstrated that pharmacological inhibition of epidermal gro...

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Detalles Bibliográficos
Autores principales: Morozevich, Galina E, Kozlova, Nadezda I, Ushakova, Natalia A, Preobrazhenskaya, Marina E, Berman, Albert E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384437/
https://www.ncbi.nlm.nih.gov/pubmed/22626691

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