Cargando…
Inhibition of Chondrosarcoma Growth by mTOR Inhibitor in an In Vivo Syngeneic Rat Model
BACKGROUND: Chondrosarcomas are the second most frequent primary malignant type of bone tumor. No effective systemic treatment has been identified in advanced or adjuvant phases for chondrosarcoma. The aim of the present study was to determine the antitumor effects of doxorubicin and everolimus, an...
Autores principales: | Perez, Jennifer, Decouvelaere, Anne Valérie, Pointecouteau, Thomas, Pissaloux, Daniel, Michot, Jean Philippe, Besse, Anthony, Blay, Jean Yves, Dutour, Aurélie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384598/ https://www.ncbi.nlm.nih.gov/pubmed/22761648 http://dx.doi.org/10.1371/journal.pone.0032458 |
Ejemplares similares
-
miRNA Profiling: How to Bypass the Current Difficulties in the Diagnosis and Treatment of Sarcomas
por: Gougelet, Angélique, et al.
Publicado: (2011) -
The immune landscape of chondrosarcoma reveals an immunosuppressive environment in the dedifferentiated subtypes and exposes CSFR1+ macrophages as a promising therapeutic target
por: Iseulys, Richert, et al.
Publicado: (2019) -
Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma
por: de Jong, Yvonne, et al.
Publicado: (2018) -
Exploration of the chondrosarcoma metabolome; the mTOR pathway as an important pro-survival pathway
por: Addie, Ruben D., et al.
Publicado: (2019) -
Radiotherapy in bone sarcoma: the quest for better treatment option
por: Locquet, Marie-Anaïs, et al.
Publicado: (2023)