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Development of AAVLP(HPV16/31L2) Particles as Broadly Protective HPV Vaccine Candidate
The human papillomavirus (HPV) minor capsid protein L2 is a promising candidate for a broadly protective HPV vaccine yet the titers obtained in most experimental systems are rather low. Here we examine the potential of empty AAV2 particles (AAVLPs), assembled from VP3 alone, for display of L2 epitop...
Autores principales: | Nieto, Karen, Weghofer, Margit, Sehr, Peter, Ritter, Mirko, Sedlmeier, Sebastian, Karanam, Balasubramanyam, Seitz, Hanna, Müller, Martin, Kellner, Markus, Hörer, Markus, Michaelis, Uwe, Roden, Richard B. S., Gissmann, Lutz, Kleinschmidt, Jürgen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384601/ https://www.ncbi.nlm.nih.gov/pubmed/22761884 http://dx.doi.org/10.1371/journal.pone.0039741 |
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