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Krüppel-Like Factor 8 Is a New Wnt/Beta-Catenin Signaling Target Gene and Regulator in Hepatocellular Carcinoma

Krüppel-like factor 8 (KLF8) plays important role in cell cycle and oncogenic transformation. Here we report the mechanisms by which KLF8 crosstalks with Wnt/β-catenin signaling pathway and regulates hepatocellular carcinoma (HCC) cells proliferation. We show that overexpression of KLF8 and nucleus...

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Detalles Bibliográficos
Autores principales: Yang, Tian, Cai, Sheng-Yun, Zhang, Jin, Lu, Jun-Hua, Lin, Chuan, Zhai, Jian, Wu, Meng-Chao, Shen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384617/
https://www.ncbi.nlm.nih.gov/pubmed/22761862
http://dx.doi.org/10.1371/journal.pone.0039668