Cargando…

Regression of Atherosclerosis Is Characterized by Broad Changes in the Plaque Macrophage Transcriptome

We have developed a mouse model of atherosclerotic plaque regression in which an atherosclerotic aortic arch from a hyperlipidemic donor is transplanted into a normolipidemic recipient, resulting in rapid elimination of cholesterol and monocyte-derived macrophage cells (CD68+) from transplanted vess...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feig, Jonathan E., Vengrenyuk, Yuliya, Reiser, Vladimir, Wu, Chaowei, Statnikov, Alexander, Aliferis, Constantin F., Garabedian, Michael J., Fisher, Edward A., Puig, Oscar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384622/ https://www.ncbi.nlm.nih.gov/pubmed/22761902 http://dx.doi.org/10.1371/journal.pone.0039790

Ejemplares similares

Epigenome-Guided Analysis of the Transcriptome of Plaque Macrophages during Atherosclerosis Regression Reveals Activation of the Wnt Signaling Pathway
por: Ramsey, Stephen A., et al.
Publicado: (2014)

Statins Promote the Regression of Atherosclerosis via Activation of the CCR7-Dependent Emigration Pathway in Macrophages
por: Feig, Jonathan E., et al.
Publicado: (2011)

Macrophages, dendritic cells, and regression of atherosclerosis
por: Feig, Jonathan E., et al.
Publicado: (2012)

Analysis and Computational Dissection of Molecular Signature Multiplicity
por: Statnikov, Alexander, et al.
Publicado: (2010)

A comprehensive comparison of random forests and support vector machines for microarray-based cancer classification
por: Statnikov, Alexander, et al.
Publicado: (2008)

Effects of Environment, Genetics and Data Analysis Pitfalls in an Esophageal Cancer Genome-Wide Association Study
por: Statnikov, Alexander, et al.
Publicado: (2007)

Challenges in the Analysis of Mass-Throughput Data: A Technical Commentary from the Statistical Machine Learning Perspective
por: Aliferis, Constantin F., et al.
Publicado: (2007)

The FAST-AIMS Clinical Mass Spectrometry Analysis System
por: Fananapazir, Nafeh, et al.
Publicado: (2009)

Macrophages in Atherosclerosis Regression
por: Barrett, Tessa J.
Publicado: (2020)

Plaque Calcification During Atherosclerosis Progression and Regression
por: Shioi, Atsushi, et al.
Publicado: (2018)

An Evaluation of Active Learning Causal Discovery Methods for Reverse-Engineering Local Causal Pathways of Gene Regulation
por: Ma, Sisi, et al.
Publicado: (2016)

Dynamic Aspects of Macrophage Polarization during Atherosclerosis Progression and Regression
por: Peled, Michael, et al.
Publicado: (2014)

New methods for separating causes from effects in genomics data
por: Statnikov, Alexander, et al.
Publicado: (2012)

Plaque characteristics and biomarkers predicting regression and progression of carotid atherosclerosis
por: Khan, Faisel, et al.
Publicado: (2022)

The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting macrophage emigration from plaques
por: van Gils, Janine M, et al.
Publicado: (2012)

Diabetes Adversely Affects Macrophages During Atherosclerotic Plaque Regression in Mice
por: Parathath, Saj, et al.
Publicado: (2011)

2290: Control of atherosclerosis regression by LXRα S198 phosphorylation
por: Shrestha, Elina, et al.
Publicado: (2018)

Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques
por: Yang, Chongbo, et al.
Publicado: (2019)

Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis
por: Beldman, Thijs J., et al.
Publicado: (2017)

Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering
por: Härdtner, Carmen, et al.
Publicado: (2020)

Changes in transcriptome of macrophages in atherosclerosis
por: Chistiakov, Dimitry A, et al.
Publicado: (2015)

The Role of Monocytes and Macrophages in Human Atherosclerosis, Plaque Neoangiogenesis, and Atherothrombosis
por: Moroni, Francesco, et al.
Publicado: (2019)

Correction: Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques
por: Yang, Chongbo, et al.
Publicado: (2022)

Expanding the Understanding of Biases in Development of Clinical-Grade Molecular Signatures: A Case Study in Acute Respiratory Viral Infections
por: Lytkin, Nikita I., et al.
Publicado: (2011)

Using gene expression profiles from peripheral blood to identify asymptomatic responses to acute respiratory viral infections
por: Statnikov, Alexander, et al.
Publicado: (2010)

Factors Influencing the Statistical Power of Complex Data Analysis Protocols for Molecular Signature Development from Microarray Data
por: Aliferis, Constantin F., et al.
Publicado: (2009)

Imaging of Oxidation-Specific Epitopes in Atherosclerosis and Macrophage-Rich Vulnerable Plaques
por: Briley-Saebo, Karen C., et al.
Publicado: (2010)

Characteristics of plaque lipid-associated macrophages and their possible roles in the pathogenesis of atherosclerosis
por: Kim, Kyeongdae, et al.
Publicado: (2022)

Loss of PRMT2 in myeloid cells in normoglycemic mice phenocopies impaired regression of atherosclerosis in diabetic mice
por: Vurusaner, Beyza, et al.
Publicado: (2022)

Urotensin II Enhances Advanced Aortic Atherosclerosis Formation and Delays Plaque Regression in Hyperlipidemic Rabbits
por: Yu, Qingqing, et al.
Publicado: (2023)

Causal graph-based analysis of genome-wide association data in rheumatoid arthritis
por: Alekseyenko, Alexander V, et al.
Publicado: (2011)

Macrophages and Their Role in Atherosclerosis: Pathophysiology and Transcriptome Analysis
por: Bobryshev, Yuri V., et al.
Publicado: (2016)

Plaque regression and plaque stabilisation in cardiovascular diseases
por: Dave, Tarun, et al.
Publicado: (2013)

A Proteomic Study of Atherosclerotic Plaques in Men with Coronary Atherosclerosis
por: Stakhneva, Ekaterina M., et al.
Publicado: (2019)

The Relation between Atherosclerosis Plaque Composition and Plaque Rupture
por: Babaniamansour, Parto, et al.
Publicado: (2020)

Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype
por: Cardilo-Reis, Larissa, et al.
Publicado: (2012)

The incretin hormone GIP is upregulated in patients with atherosclerosis and stabilizes plaques in ApoE(−/−) mice by blocking monocyte/macrophage activation
por: Kahles, Florian, et al.
Publicado: (2018)

Microbiomic Signatures of Psoriasis: Feasibility and Methodology Comparison
por: Statnikov, Alexander, et al.
Publicado: (2013)

Cholesterol Diet Withdrawal Leads to an Initial Plaque Instability and Subsequent Regression of Accelerated Iliac Artery Atherosclerosis in Rabbits
por: Khanna, Vivek, et al.
Publicado: (2013)

Regression of Plaque Enhancement Within Symptomatic Middle Cerebral Artery Atherosclerosis: A High-Resolution MRI Study
por: Yang, Wen-Jie, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_msglasiouohose9fr6il61ito1