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Glucocorticoid and Estrogen Receptors Are Reduced in Mitochondria of Lung Epithelial Cells in Asthma
Mitochondrial glucocorticoid (mtGR) and estrogen (mtER) receptors participate in the coordination of the cell’s energy requirement and in the mitochondrial oxidative phosphorylation enzyme (OXPHOS) biosynthesis, affecting reactive oxygen species (ROS) generation and induction of apoptosis. Although...
Autores principales: | Simoes, Davina C. M., Psarra, Anna-Maria G., Mauad, Thais, Pantou, Ioanna, Roussos, Charis, Sekeris, Constantine E., Gratziou, Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384641/ https://www.ncbi.nlm.nih.gov/pubmed/22761735 http://dx.doi.org/10.1371/journal.pone.0039183 |
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