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Glucocorticoid and Estrogen Receptors Are Reduced in Mitochondria of Lung Epithelial Cells in Asthma

Mitochondrial glucocorticoid (mtGR) and estrogen (mtER) receptors participate in the coordination of the cell’s energy requirement and in the mitochondrial oxidative phosphorylation enzyme (OXPHOS) biosynthesis, affecting reactive oxygen species (ROS) generation and induction of apoptosis. Although...

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Detalles Bibliográficos
Autores principales: Simoes, Davina C. M., Psarra, Anna-Maria G., Mauad, Thais, Pantou, Ioanna, Roussos, Charis, Sekeris, Constantine E., Gratziou, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384641/
https://www.ncbi.nlm.nih.gov/pubmed/22761735
http://dx.doi.org/10.1371/journal.pone.0039183

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