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Two Mechanisms Regulate Keratin K15 Expression In Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signalling
BACKGROUND: Keratin 15 (K15) is a type I keratin that is used as a marker of stem cells. Its expression is restricted to the basal layer of stratified epithelia, and the bulge in hair follicles. However, in certain clinical situations including oral lichen planus, K15 is induced in suprabasal layers...
Autores principales: | Bose, Amrita, Teh, Muy-Teck, Hutchison, Iain L., Wan, Hong, Leigh, Irene M., Waseem, Ahmad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384677/ https://www.ncbi.nlm.nih.gov/pubmed/22761689 http://dx.doi.org/10.1371/journal.pone.0038599 |
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