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Lung Infection Caused by Mycobacterium riyadhense Confused with Mycobacterium tuberculosis: The First Case in Korea
A slowly growing, non-chromogenic mycobacterial strain was isolated from sputum and bronchial lavage fluid samples of a patient presenting with productive cough, blood-tinged sputum, low-grade fever, and weakness. A positive acid-fast bacilli sputum smear result prompted the initiation of an anti-tu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Laboratory Medicine
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384813/ https://www.ncbi.nlm.nih.gov/pubmed/22779073 http://dx.doi.org/10.3343/alm.2012.32.4.298 |
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author | Choi, Jung-In Lim, Ji-Hun Kim, Sung-Ryul Lee, Seon Ho Park, Jae-Sun Seo, Kwang Won Jeon, Jae Bum Jeong, Joseph |
author_facet | Choi, Jung-In Lim, Ji-Hun Kim, Sung-Ryul Lee, Seon Ho Park, Jae-Sun Seo, Kwang Won Jeon, Jae Bum Jeong, Joseph |
author_sort | Choi, Jung-In |
collection | PubMed |
description | A slowly growing, non-chromogenic mycobacterial strain was isolated from sputum and bronchial lavage fluid samples of a patient presenting with productive cough, blood-tinged sputum, low-grade fever, and weakness. A positive acid-fast bacilli sputum smear result prompted the initiation of an anti-tuberculosis regimen. Multiplex real-time PCR showed a negative result for Mycobacterium tuberculosis complex and a positive result for nontuberculous mycobacteria. The DNA chip test confirmed this organism as a member of the genus Mycobacterium, but could not specify the species. Interestingly, the mycolic acid patterns obtained by HPLC nearly overlapped with those of M. simulans. The sequences of the Mycobacterium 16S rRNA gene and 16S-23S internal transcribed spacer region were unique and were found to have 100% similarity with those of M. riyadhense. After a review of the literature, we report this case as the first Korean case of M. riyadhense lung infection. |
format | Online Article Text |
id | pubmed-3384813 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | The Korean Society for Laboratory Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-33848132012-07-10 Lung Infection Caused by Mycobacterium riyadhense Confused with Mycobacterium tuberculosis: The First Case in Korea Choi, Jung-In Lim, Ji-Hun Kim, Sung-Ryul Lee, Seon Ho Park, Jae-Sun Seo, Kwang Won Jeon, Jae Bum Jeong, Joseph Ann Lab Med Case Report A slowly growing, non-chromogenic mycobacterial strain was isolated from sputum and bronchial lavage fluid samples of a patient presenting with productive cough, blood-tinged sputum, low-grade fever, and weakness. A positive acid-fast bacilli sputum smear result prompted the initiation of an anti-tuberculosis regimen. Multiplex real-time PCR showed a negative result for Mycobacterium tuberculosis complex and a positive result for nontuberculous mycobacteria. The DNA chip test confirmed this organism as a member of the genus Mycobacterium, but could not specify the species. Interestingly, the mycolic acid patterns obtained by HPLC nearly overlapped with those of M. simulans. The sequences of the Mycobacterium 16S rRNA gene and 16S-23S internal transcribed spacer region were unique and were found to have 100% similarity with those of M. riyadhense. After a review of the literature, we report this case as the first Korean case of M. riyadhense lung infection. The Korean Society for Laboratory Medicine 2012-07 2012-06-20 /pmc/articles/PMC3384813/ /pubmed/22779073 http://dx.doi.org/10.3343/alm.2012.32.4.298 Text en © The Korean Society for Laboratory Medicine. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Choi, Jung-In Lim, Ji-Hun Kim, Sung-Ryul Lee, Seon Ho Park, Jae-Sun Seo, Kwang Won Jeon, Jae Bum Jeong, Joseph Lung Infection Caused by Mycobacterium riyadhense Confused with Mycobacterium tuberculosis: The First Case in Korea |
title | Lung Infection Caused by Mycobacterium riyadhense Confused with Mycobacterium tuberculosis: The First Case in Korea |
title_full | Lung Infection Caused by Mycobacterium riyadhense Confused with Mycobacterium tuberculosis: The First Case in Korea |
title_fullStr | Lung Infection Caused by Mycobacterium riyadhense Confused with Mycobacterium tuberculosis: The First Case in Korea |
title_full_unstemmed | Lung Infection Caused by Mycobacterium riyadhense Confused with Mycobacterium tuberculosis: The First Case in Korea |
title_short | Lung Infection Caused by Mycobacterium riyadhense Confused with Mycobacterium tuberculosis: The First Case in Korea |
title_sort | lung infection caused by mycobacterium riyadhense confused with mycobacterium tuberculosis: the first case in korea |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384813/ https://www.ncbi.nlm.nih.gov/pubmed/22779073 http://dx.doi.org/10.3343/alm.2012.32.4.298 |
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