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Spatiotemporal Dysfunction of the Vascular Permeability Barrier in Transgenic Mice with Sickle Cell Disease

Sickle cell disease (SCD) is characterized by chronic intravascular hemolysis that generates excess cell-free hemoglobin in the blood circulation. Hemoglobin causes multiple endothelial dysfunctions including increased vascular permeability, impaired reactivity to vasoactive agonists, and increased...

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Detalles Bibliográficos
Autores principales:	Ghosh, Samit, Tan, Fang, Ofori-Acquah, Solomon F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384933/ https://www.ncbi.nlm.nih.gov/pubmed/22778926 http://dx.doi.org/10.1155/2012/582018

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