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Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread

Gastric cancer often carries a poor prognosis, with an estimated 740,000 deaths from the malignancy occurring yearly worldwide (Dicken et al., 2005). The mortality of disease is largely dependent on the extent of tumor spread, as gastric cancer has a predilection to metastasize to other visceral sec...

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Autores principales: Shah, Mitanshu, Prasad, Apsara, Rajan, Dhyan, Tan, Christopher B., Shah, Mansi, Raghavan, Pooja, Mustacchia, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384973/
https://www.ncbi.nlm.nih.gov/pubmed/22761626
http://dx.doi.org/10.1155/2012/651232
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author Shah, Mitanshu
Prasad, Apsara
Rajan, Dhyan
Tan, Christopher B.
Shah, Mansi
Raghavan, Pooja
Mustacchia, Paul
author_facet Shah, Mitanshu
Prasad, Apsara
Rajan, Dhyan
Tan, Christopher B.
Shah, Mansi
Raghavan, Pooja
Mustacchia, Paul
author_sort Shah, Mitanshu
collection PubMed
description Gastric cancer often carries a poor prognosis, with an estimated 740,000 deaths from the malignancy occurring yearly worldwide (Dicken et al., 2005). The mortality of disease is largely dependent on the extent of tumor spread, as gastric cancer has a predilection to metastasize to other visceral secondaries via hematogenous and lymphatic dissemination. Direct invasion of a gastric adenocarcinoma to adjacent organs secondary to gastric wall perforation does occur; however, it is often present in the setting of advanced disease. Rarely does direct tumor invasion to adjacent organs from a gastric adenocarcinoma present as the initial manifestation of extranodal tumor spread. We present a case of a 40-year-old male with direct tumor extension to the liver as an initial presentation of extranodal tumor spread from a gastric adenocarcinoma. Clinicians should be aware of such an occurrence, as treatment modalities in direct liver extension from a gastric adenocarcinoma vary and may be directed towards palliation rather than curative intent.
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spelling pubmed-33849732012-07-03 Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread Shah, Mitanshu Prasad, Apsara Rajan, Dhyan Tan, Christopher B. Shah, Mansi Raghavan, Pooja Mustacchia, Paul Case Rep Med Case Report Gastric cancer often carries a poor prognosis, with an estimated 740,000 deaths from the malignancy occurring yearly worldwide (Dicken et al., 2005). The mortality of disease is largely dependent on the extent of tumor spread, as gastric cancer has a predilection to metastasize to other visceral secondaries via hematogenous and lymphatic dissemination. Direct invasion of a gastric adenocarcinoma to adjacent organs secondary to gastric wall perforation does occur; however, it is often present in the setting of advanced disease. Rarely does direct tumor invasion to adjacent organs from a gastric adenocarcinoma present as the initial manifestation of extranodal tumor spread. We present a case of a 40-year-old male with direct tumor extension to the liver as an initial presentation of extranodal tumor spread from a gastric adenocarcinoma. Clinicians should be aware of such an occurrence, as treatment modalities in direct liver extension from a gastric adenocarcinoma vary and may be directed towards palliation rather than curative intent. Hindawi Publishing Corporation 2012 2012-06-17 /pmc/articles/PMC3384973/ /pubmed/22761626 http://dx.doi.org/10.1155/2012/651232 Text en Copyright © 2012 Mitanshu Shah et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Shah, Mitanshu
Prasad, Apsara
Rajan, Dhyan
Tan, Christopher B.
Shah, Mansi
Raghavan, Pooja
Mustacchia, Paul
Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread
title Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread
title_full Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread
title_fullStr Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread
title_full_unstemmed Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread
title_short Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread
title_sort direct liver invasion from a gastric adenocarcinoma as an initial presentation of extranodal tumor spread
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384973/
https://www.ncbi.nlm.nih.gov/pubmed/22761626
http://dx.doi.org/10.1155/2012/651232
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