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Cigarette Smoke Extract Stimulates Rat Pulmonary Artery Smooth Muscle Cell Proliferation via PKC-PDGFB Signaling

Accumulating evidence suggests a direct role for cigarette smoke in pulmonary vascular remodeling, which contributes to the development of pulmonary hypertension. However, the molecular mechanisms underlying this process remain poorly understood. Platelet-derived growth factor (PDGF) is a potential...

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Detalles Bibliográficos
Autores principales: Xing, Ai-ping, Du, Yong-cheng, Hu, Xiao-yun, Xu, Jian-ying, Zhang, Huan-ping, Li, Yi, Nie, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384980/
https://www.ncbi.nlm.nih.gov/pubmed/22754279
http://dx.doi.org/10.1155/2012/534384

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