Inbreeding as a cause for deafness: Dadhkai study

BACKGROUND: We report on the higher prevalence of deaf-mutes from a village in Jammu and Kashmir State of India. MATERIALS AND METHODS: A cross-sectional study among 79 deaf mutes using pedigree analysis, audiometry, imaging and molecular analysis. RESULTS: A high rate of hereditary deafness with 79...

Descripción completa

Detalles Bibliográficos
Autores principales: Razdan, Sushil, Raina, Sunil Kumar, Pandita, Kamal K., Razdan, Shiveta, Nanda, Renu, Kaul, Rajni, Dogra, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385183/
https://www.ncbi.nlm.nih.gov/pubmed/22754225
http://dx.doi.org/10.4103/0971-6866.96655
Descripción
Sumario:BACKGROUND: We report on the higher prevalence of deaf-mutes from a village in Jammu and Kashmir State of India. MATERIALS AND METHODS: A cross-sectional study among 79 deaf mutes using pedigree analysis, audiometry, imaging and molecular analysis. RESULTS: A high rate of hereditary deafness with 79 individuals diagnosed to be suffering from non-syndrome deafness in a total population of 2452 individuals residing in the village. INTERPRETATION: Flourishing of intermarriages led to a population with high prevalence of deafness

Ejemplares similares