Inbreeding as a cause for deafness: Dadhkai study

BACKGROUND: We report on the higher prevalence of deaf-mutes from a village in Jammu and Kashmir State of India. MATERIALS AND METHODS: A cross-sectional study among 79 deaf mutes using pedigree analysis, audiometry, imaging and molecular analysis. RESULTS: A high rate of hereditary deafness with 79...

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Detalles Bibliográficos
Autores principales: Razdan, Sushil, Raina, Sunil Kumar, Pandita, Kamal K., Razdan, Shiveta, Nanda, Renu, Kaul, Rajni, Dogra, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385183/
https://www.ncbi.nlm.nih.gov/pubmed/22754225
http://dx.doi.org/10.4103/0971-6866.96655
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author Razdan, Sushil
Raina, Sunil Kumar
Pandita, Kamal K.
Razdan, Shiveta
Nanda, Renu
Kaul, Rajni
Dogra, Sandeep
author_facet Razdan, Sushil
Raina, Sunil Kumar
Pandita, Kamal K.
Razdan, Shiveta
Nanda, Renu
Kaul, Rajni
Dogra, Sandeep
author_sort Razdan, Sushil
collection PubMed
description BACKGROUND: We report on the higher prevalence of deaf-mutes from a village in Jammu and Kashmir State of India. MATERIALS AND METHODS: A cross-sectional study among 79 deaf mutes using pedigree analysis, audiometry, imaging and molecular analysis. RESULTS: A high rate of hereditary deafness with 79 individuals diagnosed to be suffering from non-syndrome deafness in a total population of 2452 individuals residing in the village. INTERPRETATION: Flourishing of intermarriages led to a population with high prevalence of deafness
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spelling pubmed-33851832012-07-02 Inbreeding as a cause for deafness: Dadhkai study Razdan, Sushil Raina, Sunil Kumar Pandita, Kamal K. Razdan, Shiveta Nanda, Renu Kaul, Rajni Dogra, Sandeep Indian J Hum Genet Original Article BACKGROUND: We report on the higher prevalence of deaf-mutes from a village in Jammu and Kashmir State of India. MATERIALS AND METHODS: A cross-sectional study among 79 deaf mutes using pedigree analysis, audiometry, imaging and molecular analysis. RESULTS: A high rate of hereditary deafness with 79 individuals diagnosed to be suffering from non-syndrome deafness in a total population of 2452 individuals residing in the village. INTERPRETATION: Flourishing of intermarriages led to a population with high prevalence of deafness Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3385183/ /pubmed/22754225 http://dx.doi.org/10.4103/0971-6866.96655 Text en Copyright: © Indian Journal of Human Genetics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Razdan, Sushil
Raina, Sunil Kumar
Pandita, Kamal K.
Razdan, Shiveta
Nanda, Renu
Kaul, Rajni
Dogra, Sandeep
Inbreeding as a cause for deafness: Dadhkai study
title Inbreeding as a cause for deafness: Dadhkai study
title_full Inbreeding as a cause for deafness: Dadhkai study
title_fullStr Inbreeding as a cause for deafness: Dadhkai study
title_full_unstemmed Inbreeding as a cause for deafness: Dadhkai study
title_short Inbreeding as a cause for deafness: Dadhkai study
title_sort inbreeding as a cause for deafness: dadhkai study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385183/
https://www.ncbi.nlm.nih.gov/pubmed/22754225
http://dx.doi.org/10.4103/0971-6866.96655
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