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A Novel Extraction Method and Some Physicochemical Properties of Extractives of Irvingia Gabonensis seeds

The plant Irvingia gabonensis contains lipids and polymer extractives that can be a good source of excipients for oral pharmaceutical formulations. These constituents are usually extracted from the seeds with the aid of either organic solvents or enzymes. The purpose of this paper was to describe a...

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Autores principales: Ogaji, Ikoni J, Nan, Anjan, Hoag, Stephen W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385219/
https://www.ncbi.nlm.nih.gov/pubmed/22754256
http://dx.doi.org/10.4103/0975-1483.96612
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author Ogaji, Ikoni J
Nan, Anjan
Hoag, Stephen W
author_facet Ogaji, Ikoni J
Nan, Anjan
Hoag, Stephen W
author_sort Ogaji, Ikoni J
collection PubMed
description The plant Irvingia gabonensis contains lipids and polymer extractives that can be a good source of excipients for oral pharmaceutical formulations. These constituents are usually extracted from the seeds with the aid of either organic solvents or enzymes. The purpose of this paper was to describe a novel, simpler, cheaper, and safer method for the simultaneous extraction of lipids and gum from I. gabonensis. A 100.0 g of seeds of I. gabonensis in 200 mL deionized water was heated at 78°C in the presence of 2.0 g sodium chloride for 1 h, and the mixture was allowed to stand for the lipids to be separated and removed by filtration. The samples were air dried at 25–30°C. The liquid fraction was centrifuged at 3445 rpm for 30 min, and the supernatant portion containing the gum was freeze dried. The samples were investigated for their true, bulk, and tapped densities as well as particle size and particle size distributions. The rheological, and near infrared absorption spectra as well as thermal behavior of the samples were also studied. The lipid and the polymeric components of I. gabonensis seeds were successfully extracted simultaneously. The true densities of the fatty and gum components were, respectively, 1.000 and 1.544 g/cm(3). The melting point of the fat was 40°C and T(g) of the gum was 232°C. These values were similar to those described in the literature for the components using the traditional method, demonstrating the effectiveness and efficiency of this simple novel method.
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spelling pubmed-33852192012-07-02 A Novel Extraction Method and Some Physicochemical Properties of Extractives of Irvingia Gabonensis seeds Ogaji, Ikoni J Nan, Anjan Hoag, Stephen W J Young Pharm Pharmacognosy The plant Irvingia gabonensis contains lipids and polymer extractives that can be a good source of excipients for oral pharmaceutical formulations. These constituents are usually extracted from the seeds with the aid of either organic solvents or enzymes. The purpose of this paper was to describe a novel, simpler, cheaper, and safer method for the simultaneous extraction of lipids and gum from I. gabonensis. A 100.0 g of seeds of I. gabonensis in 200 mL deionized water was heated at 78°C in the presence of 2.0 g sodium chloride for 1 h, and the mixture was allowed to stand for the lipids to be separated and removed by filtration. The samples were air dried at 25–30°C. The liquid fraction was centrifuged at 3445 rpm for 30 min, and the supernatant portion containing the gum was freeze dried. The samples were investigated for their true, bulk, and tapped densities as well as particle size and particle size distributions. The rheological, and near infrared absorption spectra as well as thermal behavior of the samples were also studied. The lipid and the polymeric components of I. gabonensis seeds were successfully extracted simultaneously. The true densities of the fatty and gum components were, respectively, 1.000 and 1.544 g/cm(3). The melting point of the fat was 40°C and T(g) of the gum was 232°C. These values were similar to those described in the literature for the components using the traditional method, demonstrating the effectiveness and efficiency of this simple novel method. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3385219/ /pubmed/22754256 http://dx.doi.org/10.4103/0975-1483.96612 Text en Copyright: © Journal of Young Pharmacists http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Pharmacognosy
Ogaji, Ikoni J
Nan, Anjan
Hoag, Stephen W
A Novel Extraction Method and Some Physicochemical Properties of Extractives of Irvingia Gabonensis seeds
title A Novel Extraction Method and Some Physicochemical Properties of Extractives of Irvingia Gabonensis seeds
title_full A Novel Extraction Method and Some Physicochemical Properties of Extractives of Irvingia Gabonensis seeds
title_fullStr A Novel Extraction Method and Some Physicochemical Properties of Extractives of Irvingia Gabonensis seeds
title_full_unstemmed A Novel Extraction Method and Some Physicochemical Properties of Extractives of Irvingia Gabonensis seeds
title_short A Novel Extraction Method and Some Physicochemical Properties of Extractives of Irvingia Gabonensis seeds
title_sort novel extraction method and some physicochemical properties of extractives of irvingia gabonensis seeds
topic Pharmacognosy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385219/
https://www.ncbi.nlm.nih.gov/pubmed/22754256
http://dx.doi.org/10.4103/0975-1483.96612
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