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Nicolau Syndrome after Intramuscular Injection: 3 Cases
Nicolau syndrome is a rare complication of intramuscular injection consisting of ischemic necrosis of skin, soft tissue, and muscular tissue that arises locoregionally. The characteristic pattern is pain around the injection site, developing into erythema, a livedoid dermatitis patch, and necrosis o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Plastic and Reconstructive Surgeons
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385328/ https://www.ncbi.nlm.nih.gov/pubmed/22783535 http://dx.doi.org/10.5999/aps.2012.39.3.249 |
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author | Kim, Seok-Kwun Kim, Tae-Heon Lee, Keun-Cheol |
author_facet | Kim, Seok-Kwun Kim, Tae-Heon Lee, Keun-Cheol |
author_sort | Kim, Seok-Kwun |
collection | PubMed |
description | Nicolau syndrome is a rare complication of intramuscular injection consisting of ischemic necrosis of skin, soft tissue, and muscular tissue that arises locoregionally. The characteristic pattern is pain around the injection site, developing into erythema, a livedoid dermatitis patch, and necrosis of the skin, subcutaneous fat, and muscle tissue. Three patients were injected with drugs (diclofenac sodium, ketoprofen, meperidine) for pain relief. Three patients complained of pain, and a skin lesion was observed, after which necrosis developed on their buttocks. Each patient underwent debridement and coverage. The wound healed uneventfully. We report three cases of Nicolau syndrome in the buttocks following diclofenac intramuscular injection. |
format | Online Article Text |
id | pubmed-3385328 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | The Korean Society of Plastic and Reconstructive Surgeons |
record_format | MEDLINE/PubMed |
spelling | pubmed-33853282012-07-10 Nicolau Syndrome after Intramuscular Injection: 3 Cases Kim, Seok-Kwun Kim, Tae-Heon Lee, Keun-Cheol Arch Plast Surg Case Report Nicolau syndrome is a rare complication of intramuscular injection consisting of ischemic necrosis of skin, soft tissue, and muscular tissue that arises locoregionally. The characteristic pattern is pain around the injection site, developing into erythema, a livedoid dermatitis patch, and necrosis of the skin, subcutaneous fat, and muscle tissue. Three patients were injected with drugs (diclofenac sodium, ketoprofen, meperidine) for pain relief. Three patients complained of pain, and a skin lesion was observed, after which necrosis developed on their buttocks. Each patient underwent debridement and coverage. The wound healed uneventfully. We report three cases of Nicolau syndrome in the buttocks following diclofenac intramuscular injection. The Korean Society of Plastic and Reconstructive Surgeons 2012-05 2012-05-10 /pmc/articles/PMC3385328/ /pubmed/22783535 http://dx.doi.org/10.5999/aps.2012.39.3.249 Text en Copyright © 2012 The Korean Society of Plastic and Reconstructive Surgeons http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kim, Seok-Kwun Kim, Tae-Heon Lee, Keun-Cheol Nicolau Syndrome after Intramuscular Injection: 3 Cases |
title | Nicolau Syndrome after Intramuscular Injection: 3 Cases |
title_full | Nicolau Syndrome after Intramuscular Injection: 3 Cases |
title_fullStr | Nicolau Syndrome after Intramuscular Injection: 3 Cases |
title_full_unstemmed | Nicolau Syndrome after Intramuscular Injection: 3 Cases |
title_short | Nicolau Syndrome after Intramuscular Injection: 3 Cases |
title_sort | nicolau syndrome after intramuscular injection: 3 cases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385328/ https://www.ncbi.nlm.nih.gov/pubmed/22783535 http://dx.doi.org/10.5999/aps.2012.39.3.249 |
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